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Table 1 Study and patient characteristics – switching and discontinuation patterns among triptan users

From: The burden of medication overuse headache and patterns of switching and discontinuation among triptan users: a systematic literature review

Citation

Country (Study period)

Study type

Study name/ database

Sample

Subgroup

n

Mean age, yrs

% female

Alam, 2018 [35]

US (2016)

Multicenter cross-sectional, Survey

MAST study

Current users

Overall

15,133

43.1

73.0

Chen, 2014 [36]

Taiwan (2005-2008)

Database study

NHIR Database

Incident users

Overall

13,951

41.3

77.0

Fischer, 2016 [37]

Austria (2009-2012)

Single center chart review

Outpatient clinic, U of Innsbruck

Incident users (first/new agent)

Overall

126

37.2

88.1

Katic, 2011 [38]

US (2001-2005)

Database study

i3 InVision Data Mart

Incident users

Overall

40,892

37.8

78.9

Lombard, 2018 [39]

US (2012-2014)

Database study

Truven MarketScan

Incident users

Overall

124,556

30.0-49.0

81.0

Ng-Mak, 2012 [40]

EU (2006-2008)

Database study

IMS Disease Analyzer

Incident users

UK

3618

41.3

75.6

France

2051

38.9

75.8

Germany

954

41.6

78.0

Serrano, 2013 [41]

US (2005-2009)

Multicenter prospective, Survey

AMPP study

Current users

Consistency group A

700

47.3

89.0

Consistency group B

697

47.2

88.5

Consistency group C

687

47.1

88.6

  1. Consistency group A: Did not switch to another triptan in any couplet and consistently used the same triptan across years in their first eligible couplet; Consistency group B: Did not switch to an opioid/ barbiturate in any couplet and consistently used the same triptan across years in their first eligible couplet; Consistency group C: Did not switch to an NSAID in any couplet and consistently used the same triptan across years in their first eligible couplet
  2. Abbreviations: AMPP American Migraine Prevalence and Prevention, EU Europe, IMS Information Management System, MAST Migraine in America Symptoms and Treatment, NHIR National Health Insurance Research, SC Subcutaneous inj., U University, US United States, Yrs Years