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Table 2 Univariable logistic regression analysis of each indicator and diagnostic in the development cohort

From: Development and external validation of a nomogram for neurosyphilis diagnosis among non-HIV patients: a cross-sectional study

Characteristic Univariable analysis
Odds ratio 95% CI P value
Male 1·71 (0·72, 4·02) 0·222
Age 1·01 (0·98, 1·04) 0·691
Treatment before 0·53 (0·25, 1·11) 0·094
Psychiatric behaviour disorders 3·89 (1·70, 8·89) 0·001
No symptom 0·53 (0·17, 1·62) 0·263
Serum TPPA > 1:320 2·67 (0·93, 7·64) 0·068
Serum TRUST
 Negative Ref   
  1 1·93 (0·41, 9·10) 0·407
  8 4·20 (0·74, 23·91) 0·106
  16 9·00 (1·82, 44·59) 0·007
  32 22·50 (4·23, 119·77) 0·000
  64 49·50 (7·15, 342·77) < 0·0001
Serum creatine kinase 1·00 (1·00, 1·01) 0·109
 Elevated CK 4·8 (1·1, 21·8) 0·042
 Serum IgG 1·03 (0·90, 1·18) 0·687
 Serum albumin 0·95 (0·88, 1·04) 0·284
 CSF Protein 6·51 (1·77, 23·96) 0·005
   ≤ 0·45 Ref   
   > 0·45 4·80 (2·22, 10·36) < 0·0001
 CSF Glucose 0·66 (0·39, 1·09) 0·105
 CSF Nucleated cells 1·00 (0·99, 1·01) 0·899
   ≤ 5 Ref   
   > 5 2·89 (1·38, 6·08) 0·005
  1. TPPA Treponema pallidum particle agglutination assay, TRUST, Toluidine red unheated serum test; Elevated creatine kinase (CK) male ≥308, female ≥192 U/L, CSF Cerebrospinal fluid, IgG Immunoglobulin