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Table 2 DaT-SPECT visual read results of the imaged participants (N = 398)

From: Evaluating dopamine transporter imaging as an enrichment biomarker in a phase 2 Parkinson’s disease trial

Classification Activity pattern Participants, N (%)
Normal Activity in the putamen and caudate nuclei of both hemispheres is still visible 15 (3.8%)
Abnormal Activity in the region of the putamen is absent or greatly reduced in at least one hemisphere. Activity is still visible in the caudate nuclei of both hemispheres 81 (20.3%)
Activity is absent in the putamen of both hemispheres and confined to the caudate nuclei 204 (51.3%)
Activity is absent in the putamen of both hemispheres and greatly reduced in one or both caudate nuclei 98 (24.6%)
  1. DaT-SPECT dopamine transporter single-photon emission computed tomography