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Table 2 Correlation analysis between FXYD2 mRNA expression and overall survival among 516 glioma patients in CGGA

From: FXYD2 mRNA expression represents a new independent factor that affects survival of glioma patients and predicts chemosensitivity of patients to temozolomide

Parameter

Univariate Cox Regression

Multivariate Cox Regression

P value

HR

95% CI (low-up)

P value

HR

95% CI (low-up)

Sex

0.447

1.091

0.871–1.366

   

Age

0.000

1.027

1.017–1.036

0.002

1.015

1.005–1.024

Recurrent

0.000

2.117

1.690–2.651

0.000

2.118

1.672–2.684

Histopathological types (HE)

0.000

1.827

1.657–2.015

0.333

0.896

0.719–1.118

2021 WHO glade

0.000

2.804

2.377–3.308

0.000

2.717

1.914–3.856

IDH mutation status

0.000

0.321

0.256–0.403

0.025

0.712

0.529–0.958

1p/19q codeletion status

0.000

0.282

0.199–0.400

0.000

0.403

0.265–0.611

MGMT methylation_status

0.004

0.790

0.674–0.926

0.041

0.841

0.713–0.993

Complete excision

0.713

1.050

0.809-1.364

0.201

0.838

0.639–1.099

Radiotherapy

0.467

1.109

0.839–1.465

0.244

0.825

0.598–1.140

Chemotherapy

0.230

1.176

0.903–1.533

0.003

0.611

0.443–0.841

FXYD2 mRNA expression

0.000

0.469

0.374–0.589

0.018

0.959

0.927–0.993

  1. HR Hazard ratio, CI Confidence interval