Table 2 Evaluation of CT morphologic features of hypoxic-ischaemic brain injury and related diagnostic accuracy regarding poor neurologic outcomes (complete study population)
Observer A | Observer B | Observer C | Observer D | Kappa | |
|---|---|---|---|---|---|
Loss of gray and white matter distinction | 58.1% | 68.1% | 37.0% | 31.9% | 0.438 (0.373–0.503) |
Cerebral oedema | 32.6% | 60.1% | 26.8% | 28.3% | 0.471 (0.403–0.538) |
Intracranial haemorrhage | 2.2% | 2.9% | 1.4% | 0.7% | 0.185 (0.116–0.254) |
Ischaemia | 11.5% | 15.8% | 4.3% | 18.7% | 0.224 (0.155–0.293) |
Data are percentages of patients or correlation coefficients (Fleiss kappa) with 95% confidence intervals | |||||
Sensitivity | 89.9% (80.2–95.8%) | 88.4% (78.4–94.9%) | 69.6% (57.3–80.1%) | 72.5% (60.4–82.5%) | |
Specificity | 52.2% (39.8–64.4%) | 46.3% (34.0–58.9%) | 91.2% (81.8–96.7%) | 71.0% (58.8–81.3%) | |
Positive predictive value | 65.2% (59.2–70.9%) | 62.9% (57.2–68.3%) | 88.9% (78.6–94.6%) | 71.4%(62.7–78.8%) | |
Negative predictive Value | 83.7% (71.1–91.5%) | 79.5% (65.8–88.7%) | 74.7% (67.2–81.0%) | 72.0% (63.1–79.6%) | |