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Table 2 Evaluation of CT morphologic features of hypoxic-ischaemic brain injury and related diagnostic accuracy regarding poor neurologic outcomes (complete study population)

From: Prognostication of neurologic outcome using gray-white-matter-ratio in comatose patients after cardiac arrest

  Observer A Observer B Observer C Observer D Kappa
Loss of gray and white matter distinction 58.1% 68.1% 37.0% 31.9% 0.438 (0.373–0.503)
Cerebral oedema 32.6% 60.1% 26.8% 28.3% 0.471 (0.403–0.538)
Intracranial haemorrhage 2.2% 2.9% 1.4% 0.7% 0.185 (0.116–0.254)
Ischaemia 11.5% 15.8% 4.3% 18.7% 0.224 (0.155–0.293)
Data are percentages of patients or correlation coefficients (Fleiss kappa) with 95% confidence intervals
Sensitivity 89.9% (80.2–95.8%) 88.4% (78.4–94.9%) 69.6% (57.3–80.1%) 72.5% (60.4–82.5%)  
Specificity 52.2% (39.8–64.4%) 46.3% (34.0–58.9%) 91.2% (81.8–96.7%) 71.0% (58.8–81.3%)  
Positive predictive value 65.2% (59.2–70.9%) 62.9% (57.2–68.3%) 88.9% (78.6–94.6%) 71.4%(62.7–78.8%)  
Negative predictive Value 83.7% (71.1–91.5%) 79.5% (65.8–88.7%) 74.7% (67.2–81.0%) 72.0% (63.1–79.6%)  
  1. Data are proportions with 95% confidence intervals