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Table 1 Demographic and clinical data of single-RSSI patients with dysphagia and controls

From: Total magnetic resonance imaging of cerebral small vessel disease burden predicts dysphagia in patients with a single recent small subcortical infarct

Demographic and Clinical Data

Dysphagia

(n = 54)

Controls

(n = 254)

t/Z/χ2

P

Age (years)

67.54 ± 11.74, 42.00–91.00

61.00 ± 13.06, 22.00–89.00

t = − 3.40

1.00 × 10− 3

Gender male/female

37/17

176/78

χ2 = 0.01

0.91

Systolic Blood Pressure (mmHg)

152.57 ± 24.87, 105.00–220.00

147.44 ± 21.40, 100.00–230.00

t = − 1.55

0.12

Diastolic Blood Pressure (mmHg)

82.54 ± 12.11, 53.00–111.00

81.94 ± 12.89, 50.00–131.00

t = − 0.31

0.76

History of Hypertension (yes/no)

40/14

192/62

χ2 = 0.06

0.81

History of Diabetes (yes/no)

17/37

75/179

χ2 = 0.08

0.78

Smoking yes/no

12/42

68/186

χ2 = 0.48

0.49

History of AFa (yes/no)

4/50

7/247

χ2 = 2.80

0.09

Previous Stroke (yes/no)

12/42

34/220

χ2 = 2.74

0.10

Triglyceride (mmol/L)

1.33 ± 0.51, 0.49–2.55

1.67 ± 1.00, 0.38–9.11

t = 3.68

< 1.00 × 10− 3*

Total Cholesterol (mmol/L)

4.30 ± 1.03, 1.51–6.33

4.36 ± 1.05, 1.94–9.90

t = 0.38

0.70

LDLC (mmol/L)

2.62 ± 0.94, 0.63–5.01

2.65 ± 0.91, 0.65–8.11

t = 0.25

0.80

Creatinine (μmol/L)

67.78 ± 13.99, 47.30–102.00

70.24 ± 21.53, 33.20–225.30

Z = 0.34

0.73

Uric Acid (μmol/L)

282.17 ± 80.91, 138.40–472.40

312.56 ± 91.35, 92.50–648.00

t = 2.24

0.03

Fasting Blood Glucose (μmol/L)

6.03 ± 1.84, 3.92–12.76

5.98 ± 2.07, 3.34–19.60

Z = − 0.96

0.34

Homocysteineb (μmol/L)

14.13 ± 9.12, 6.20–55.60

12.84 ± 8.67, 3.40–74.40

Z = − 1.33

0.18

Hemoglobin A1cb (%)

7.08 ± 1.79, 5.20–12.10

6.72 ± 1.67, 4.90–15.10

Z = − 1.14

0.25

NIH Stroke Scale

7.78 ± 6.23, 0.00–36.00

3.23 ± 2.92, 0.00–15.00

Z = − 6.34

< 1.00 × 10− 3*

Higher CRPa

34/20

71/183

χ2 = 24.29

< 1.00 × 10− 3*

Fibrinogen (g/l)

3.18 ± 0.96, 0.75–6.18

2.61 ± 0.93, 0.75–6.77

t = − 4.06

< 1.00 × 10− 3*

Lp-PlA2b (ug/l)

139.29 ± 56.82, 63.81–311.64

157.36 ± 140.79, 56.04–800.00

Z = − 0.85

0.39

Thrombolytic (yes/no)

12/42

53/201

χ2 = 0.05

0.82

Post-stroke pneumonia (yes/no)

24/30

38/216

χ2 = 24.08

< 1.00 × 10− 3*

  1. *: p < 0.001
  2. a AF refers to atrial fibrillation, LDLC refers to low density lipoprotein cholesterol, and higher CRP refers to C-reactive protein ≥3 mg/l.
  3. b Forty four patients with dysphagia and 215 controls took part in homocysteine tests; 37 patients with dysphagia and 196 controls took part in hemoglobin A1c tests; 17 patients with dysphagia and 68 controls attended Lp-PlA2 tests
  4. Continuous data are compared by the t-test or Mann-Whitney U test and are shown as the mean ± SD, minimum and maximum values in patients with dysphagia and controls with statistical significance. Categorical variables between patients and controls are represented with statistical significance based on the chi-squared test (χ2 & p) or Fisher’s exact test (Z & p)
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BMC Neurology

ISSN: 1471-2377

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