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Table 1 Demographic and clinical data of single-RSSI patients with dysphagia and controls

From: Total magnetic resonance imaging of cerebral small vessel disease burden predicts dysphagia in patients with a single recent small subcortical infarct

Demographic and Clinical Data Dysphagia
(n = 54)
Controls
(n = 254)
t/Z/χ2 P
Age (years) 67.54 ± 11.74, 42.00–91.00 61.00 ± 13.06, 22.00–89.00 t = − 3.40 1.00 × 10− 3
Gender male/female 37/17 176/78 χ2 = 0.01 0.91
Systolic Blood Pressure (mmHg) 152.57 ± 24.87, 105.00–220.00 147.44 ± 21.40, 100.00–230.00 t = − 1.55 0.12
Diastolic Blood Pressure (mmHg) 82.54 ± 12.11, 53.00–111.00 81.94 ± 12.89, 50.00–131.00 t = − 0.31 0.76
History of Hypertension (yes/no) 40/14 192/62 χ2 = 0.06 0.81
History of Diabetes (yes/no) 17/37 75/179 χ2 = 0.08 0.78
Smoking yes/no 12/42 68/186 χ2 = 0.48 0.49
History of AFa (yes/no) 4/50 7/247 χ2 = 2.80 0.09
Previous Stroke (yes/no) 12/42 34/220 χ2 = 2.74 0.10
Triglyceride (mmol/L) 1.33 ± 0.51, 0.49–2.55 1.67 ± 1.00, 0.38–9.11 t = 3.68 < 1.00 × 10− 3*
Total Cholesterol (mmol/L) 4.30 ± 1.03, 1.51–6.33 4.36 ± 1.05, 1.94–9.90 t = 0.38 0.70
LDLC (mmol/L) 2.62 ± 0.94, 0.63–5.01 2.65 ± 0.91, 0.65–8.11 t = 0.25 0.80
Creatinine (μmol/L) 67.78 ± 13.99, 47.30–102.00 70.24 ± 21.53, 33.20–225.30 Z = 0.34 0.73
Uric Acid (μmol/L) 282.17 ± 80.91, 138.40–472.40 312.56 ± 91.35, 92.50–648.00 t = 2.24 0.03
Fasting Blood Glucose (μmol/L) 6.03 ± 1.84, 3.92–12.76 5.98 ± 2.07, 3.34–19.60 Z = − 0.96 0.34
Homocysteineb (μmol/L) 14.13 ± 9.12, 6.20–55.60 12.84 ± 8.67, 3.40–74.40 Z = − 1.33 0.18
Hemoglobin A1cb (%) 7.08 ± 1.79, 5.20–12.10 6.72 ± 1.67, 4.90–15.10 Z = − 1.14 0.25
NIH Stroke Scale 7.78 ± 6.23, 0.00–36.00 3.23 ± 2.92, 0.00–15.00 Z = − 6.34 < 1.00 × 10− 3*
Higher CRPa 34/20 71/183 χ2 = 24.29 < 1.00 × 10− 3*
Fibrinogen (g/l) 3.18 ± 0.96, 0.75–6.18 2.61 ± 0.93, 0.75–6.77 t = − 4.06 < 1.00 × 10− 3*
Lp-PlA2b (ug/l) 139.29 ± 56.82, 63.81–311.64 157.36 ± 140.79, 56.04–800.00 Z = − 0.85 0.39
Thrombolytic (yes/no) 12/42 53/201 χ2 = 0.05 0.82
Post-stroke pneumonia (yes/no) 24/30 38/216 χ2 = 24.08 < 1.00 × 10− 3*
  1. *: p < 0.001
  2. a AF refers to atrial fibrillation, LDLC refers to low density lipoprotein cholesterol, and higher CRP refers to C-reactive protein ≥3 mg/l.
  3. b Forty four patients with dysphagia and 215 controls took part in homocysteine tests; 37 patients with dysphagia and 196 controls took part in hemoglobin A1c tests; 17 patients with dysphagia and 68 controls attended Lp-PlA2 tests
  4. Continuous data are compared by the t-test or Mann-Whitney U test and are shown as the mean ± SD, minimum and maximum values in patients with dysphagia and controls with statistical significance. Categorical variables between patients and controls are represented with statistical significance based on the chi-squared test (χ2 & p) or Fisher’s exact test (Z & p)