Fig. 2

Average annual change in walking speed (m/s) by baseline markers of cerebral small vessel disease. Average annual change in walking speed (m/s) according to baseline (A) tertiles of white matter hyperintensity volume; (B) the presence of lacunes; (C) tertiles of the number of perivascular spaces; and (D) cerebral small vessel disease burden. All models were adjusted for age, sex, education, the Mini-Mental State Examination score, cardiovascular risk factors, C-reactive protein, number of chronic diseases, and cardio- and cerebrovascular diseases (n = 331)