Fig. 1

Mean UPDRS-II-ADL, UPDRS-III, and UPDRS-IV sub-items mean scores in APD and non-APD patients. Legend: p values from a paired t test indicate statistical significance; APD = Advanced Parkinsons’ Disease; non-APD = non- Advanced Parkinsons’ Disease; UPDRS-II (Unified Parkinsons’ Disease Rating Scale; ADL (Acitivity of Daily Living); for UPDRS-IV the item 32 to 34 and Item 39 are reported