Table 5 Agreement between physician’s judgment and Delphi criteria for APD (assessed on 60 APD patients)
APD Delphi criteria | Patients with concordance with physician APD classification N (%) | Cohen’s Kappa | 95%—CI |
|---|---|---|---|
Troublesome motor fluctuations, severity level (moderate or severe) | 23 (38.3%) | 0.415 | 0.284; 0.546 |
Off Time, hours/waking day (≥ 2) | 18 (30%) | 0.314 | 0.186; 0.443 |
Night-time sleep disturbances, severity level (moderate or severe) | 23 (38.3%) | 0.302 | 0.155;0.448 |
Troublesome dyskinesia, hours/waking day (≥ 2) | 27 (45%) | 0.469 | 0.335;0.603 |
Presence of non-motor fluctuations | 36 (60%) | 0.545 | 0.407; 0.683 |
Presence of “OFF” time at least every 3 h | 16 (26.7%) | 0.279 | 0.154; 0.404 |
Oral Levodopa dosing ≥ 5 times daily | 34 (56.7%) | 0.556 | 0.422; 0.690 |
Activities of daily living limitation, severity level (moderate or severe) | 25 (41.7%) | 0.421 | 0.284; 0.557 |
Falling frequency (most of the time or all the time) | 7 (11.7%) | 0.131 | 0.040; 0.222 |
Dementia, severity level (moderate or severe) | 9 (15%) | 0.125 | 0.015; 0.235 |
Psychosis, severity level (moderate or severe) | 6 (10%) | 0.084 | -0.009; 0.177 |
Overall APD classification by Delphi method | 56 (93.3%) | 0.743 | 0.633; 0.853 |