Fig. 1From: An integrated modelling methodology for estimating global incidence and prevalence of hereditary spastic paraplegia subtypes SPG4, SPG7, SPG11, and SPG15Model Logic Flow. Schematic overview of the methodology to estimate key measures. Step 1: collect information on incidence ratio and average years lived. Step 2: determine prevalence per country/region and disease type. Step 3: using additional population data, determine the patient pool per country/region and disease type. Step 4: estimate the patient pool per genetic subtype and age group for each country/region. Step 5: sample data visualizations of results from key countries and regionsBack to article page