Fig. 2From: An integrated modelling methodology for estimating global incidence and prevalence of hereditary spastic paraplegia subtypes SPG4, SPG7, SPG11, and SPG15Reported population-based prevalence. a Prevalence of Sporadic, AD, AR, and all HSP cases per 100,000 in Ortega Suero et al. 2021, and in key studies assessed in Ruano et al. 2014. Total population assessed, and number of HSP cases are represented on the right. b Reported SPG4 and SPG11 prevalence per 100,000 in Estonia, Norway and Portugal based on detailed genetic analysis. Total population assessed and number of HSP cases, divided by SPG4 and SPG11, are reported on the right. c Reported proportion of SPG4 and SPG11 in all HSP in selected studiesBack to article page