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Table 3 CSI score: headache background and characteristics

From: Cranial autonomic symptoms in migraine are related to central sensitization: a prospective study of 164 migraine patients at a tertiary headache center

 

Cases (%)

CSI score ± SD

p value

Headache background

Chronification

Complete cases

164/164 (100.0)

  

CM

111/164 (67.7)

35.6 ± 13.4

0.054

EM

53/164 (32.3)

31.4 ± 12.3

Medication overuse

Complete cases

164/164 (100.0)

  

MOH

68/164 (41.5)

35.3 ± 14.7

0.378

non-MOH

96/164 (58.5)

33.5 ± 11.9

Aura

Complete cases

164/164 (100.0)

  

with aura

27/164 (16.5)

37.1 ± 13.6

0.210

without aura

137/164 (83.5)

33.7 ± 13.0

Illness duration

Complete cases

160/164 (97.6)

  

<  5 years

11/164 (6.7)

35.4 ± 11.1

0.939

5–10 years

18/164 (11.0)

33.8 ± 17.2

>  10 years

131/164 (79.9)

33.9 ± 12.8

Sex

Complete cases

164/164 (100.0)

  

Male

33/164 (20.1)

31.1 ± 14.2

0.124

Female

131/164 (79.9)

35.0 ± 12.8

Headache characteristics

Pain location

Complete cases

159/164 (97.0)

  

Unilateral: (strictly unilateral/unilateral side variable)

53/164 (32.3)

33.7 ± 12.3

0.932

Bilateral: (always bilateral/bilateral but sometimes unilateral)

106/164 (64.6)

33.9 ± 13.4

Pain quality

Complete cases

163/164 (99.4)

  

Pulsating

110/164 (67.1)

33.7 ± 13.0

0.604

Non-pulsating

53/164 (32.3)

34.9 ± 13.4

Pain severity

Complete cases

162/164 (98.8)

  

 Maximum attack

NRS 8 out 10 or more

116/164 (70.7)

35.7 ± 12.7

0.028

 

Less than 8 out of 10

46/164 (28.0)

30.7 ± 13.4

 Usual attack

NRS 8 out 10 or more

15/164 (9.1)

33.4 ± 14.3

0.792

 

Less than 8 out of 10

147/164 (89.6)

34.3 ± 12.9

Attack duration

Complete cases

152/164 (92.7)

  

Maximum

<  24 h

61/164 (37.2)

30.6 ± 11.7

0.004††

 

24–72 h

76/164 (46.3)

34.5 ± 13.4

 

> 72 h

15/164 (9.1)

42.7 ± 13.7

 

Post hoc: <  24 h vs. > 72 h

0.004††

Usual

<  24 h

104/164 (63.4)

32.2 ± 12.1

0.077

 

24–72 h

45/164 (27.4)

37.0 ± 14.9

 

> 72 h

3/164 (1.8)

41.0 ± 13.1

Usual headache frequency (moderate to severe)

Complete cases

139/164 (84.8)

  
 

<  1 day/month

12/164 (7.3)

31.1 ± 15.1

0.069

 

1–10 days/month

106/164 (64.6)

33.8 ± 12.5

 

> 10 days/month

21/164 (12.8)

40.5 ± 15.9

  1. CSI central sensitization inventory, SD standard deviation, CM chronic migraine, EM episodic migraine, MOH medication overuse headache, NRS Numerical Rating Scale
  2. p < 0.05 ††p < 0.01