Skip to main content

Table 3 Receiver operating characteristics analysis for the optimum cut-off point for the diagnosis of perinatal asphyxia based on resistive index in Doppler sonographya

From: Using Doppler sonography resistive index for the diagnosis of perinatal asphyxia: a multi-centered study

 

AUC

Sensitivity

Specificity

PPV

NPV

PLR

NLR

ACA

 < 0.46

-

0 (0—14.8)

100 (66.4—100)

 

30.3 (15.4—49)

 

1 (1—1)

 ≤ 0.62b

0.957 (0.819 to 0.997)

95.65 (78.1—99.9)

100 (66.4—100)

100 (84.1—100)

90.9 (58—99.8)

 

0.043 (0.006—0.3)

 ≤ 0.84

-

100 (85.2—100)

0 (0—33.6)

69.7 (51—84.6)

   

MCA

 < 0.46

-

0 (0—14.8)

100 (66.4—100)

 

30.3 (15.4—49)

 

1 (1—1)

 ≤ 0.62c

0.990 (0.873 to 1)

91.30 (72.0—98.9)

100 (66.4—100)

91.2 (72.6—98.8)

100 (61.3—100)

 

0.087 (0.02—0.3)

 ≤ 0.72

-

100 (85.2—100)

0 (0—33.6)

69.7 (51—84.6)

 

1 (1—1)

0.96 (0.9—1)

BA

 < 0.45

-

0 (0—14.8)

100 (66.4—100)

 

30.3 (15.4—49)

 

1

 ≤ 0.62d

0.957 (0.819 to 0.997)

95.65 (78.1—99.9)

100 (66.4—100)

100 (84.1—100)

90.9 (58—99.8)

 

0.043 (0.006—0.3)

 ≤ 0.95

-

100 (85.2—100)

0 (0—33.6)

69.7 (51—84.6)

 

1 (1—1)

 
  1. AUC: area under curve; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; ACA: anterior cerebral artery; MCA: middle cerebral artery; BA: basilar artery
  2. aAll values are presented with their 95% confidence interval. Upper and lower limits were chosen on the ROC curve considering the highest sensitivity or specificity
  3. bthe Youden index score at this cut-off was 0.956
  4. cThe Youden index score at this cut-off was 0.956
  5. dThe Youden index score at this cut-off was 0.913