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Table 2 mGI-I draft version 1.0

From: Establishing content validity for the migraine Global Impression Item (mGI-I) assessment: a modified single-item migraine symptom severity questionnaire

 

Modified CGI-I (initial Wave 1 version)a

Patient

KFM

HCP

Instruction

The next question asks about your migraines at the moment. Please choose one answer. There is no right or wrong answer – we are interested in how you feel.

The next question asks about your family member’s migraines at the moment. Please choose one answer. There is no right or wrong answer – we are interested in how you feel.

The next question asks about your patient’s migraines at the moment. Please choose one answer. There is no right or wrong answer – we are interested in how you feel.

mGI-I

Compared to the migraines you were experiencing before starting your latest treatment, how are your migraines now?

° Very much improved

° Much improved

° A little improved

° No change

° A little worse

° Much worse

° Very much worse

Compared to the migraines your family member was experiencing before starting their latest treatment, how are their migraines now?

° Very much improved

° Much improved

° A little improved

° No change

° A little worse

° Much worse

° Very much worse

Compared to the migraines your patient was experiencing before starting their latest treatment, how are their migraines now?

° Very much improved

° Much improved

° A little improved

° No change

° A little worse

° Much worse

° Very much worse

Alternate version mGI-I stem

• Compared to the migraines you were experiencing before starting your latest treatment, how are your migraines now? (please consider the number of migraine days per month, the physical impairment associated with migraine, and the impact of migraine on everyday activities)

• Compared to the migraines your family member was experiencing before starting their latest treatment, how are their migraines now? (please consider the number of migraine days per month, the physical impairment associated with migraine, and the impact of migraine on everyday activities)

• Compared to the migraines your patient was experiencing before starting their latest treatment, how are their migraines now? (please consider the number of migraine days per month, the physical impairment associated with migraine, and the impact of migraine on everyday activities)

Alternate version mGI-I response options

° Much improved

° A little improved

° No change

° A little worse

° Much worse

° Much improved

° A little improved

° No change

° A little worse

° Much worse

° Much improved

° A little improved

° No change

° A little worse

° Much worse

  1. mGI-I Migraine global impression item, KFM Key family member, HCP Health care provider
  2. aThis initial modified version was tested in Wave 1 and then refined based on iterative feedback