Table 1 Stratification of demographics and clinical characteristics of the study population based on favorable or unfavorable outcome at 3 months in Chinese patients with acute ischemic stroke treated with mechanical thrombectomy
From: Nomogram to predict 3-month unfavorable outcome after thrombectomy for stroke
Variable | Favorable outcome (mRS 0–2) | Unfavorable outcome (mRS 3–6) | P Value |
|---|---|---|---|
Patients, n (%) | 106 | 152 | |
Demographic characteristics | |||
Age, y | 68.97 ± 12.55 | 75.63 ± 11.59 | < 0.001 |
Female, n (%) | 33(31.13) | 88(57.89) | < 0.001 |
Vascular risk factors, n (%) | |||
Hypertension | 64(60.38) | 109(71.71) | 0.057 |
Diabetes mellitus | 20(18.87) | 49(32.24) | 0.017 |
Atrial fibrillation | 28(26.42) | 55(36.18) | 0.098 |
Coronary heart disease | 22(20.75) | 42(27.63) | 0.208 |
Stroke | 20(18.87) | 40(26.32) | 0.164 |
Smoking | 51(48.11) | 49(32.24) | 0.010 |
Alcoholism | 7(6.60) | 7(4.61) | 0.486 |
Clinical data | |||
Systolic blood pressure, mm Hg | 152.35 ± 20.99 | 152.49 ± 25.82 | 0.962 |
Diastolic blood pressure, mm Hg | 85.64 ± 15.91 | 85.70 ± 14.64 | 0.977 |
Baseline NIHSS, score | 13.21 ± 6.85 | 16.28 ± 6.81 | < 0.001 |
Baseline ASPECTS, score | 8(7–9) | 7(6–8.75) | 0.039 |
Thrombolysis time window | 74(69.81) | 82(53.95) | 0.010 |
Thrombolysis | 65(61.32) | 64(42.11) | 0.002 |
Time from onset to thrombolysis, min | 106(79–135.5) | 123.5(90–189) | 0.024 |
Mechanical thrombectomy > 6 h, n (%) | 13(12.26) | 26(17.11) | 0.286 |
Time from onset to puncture, min | 200.00(135.00–273.75) | 222.50(160.00–332.50) | 0.042 |
Time from puncture to recanalization, min | 90(55.25–135.00) | 87.5(50.00–160.00) | 0.450 |
General Anesthesia | 29(27.36) | 41(26.97) | 0.945 |
Bridging therapy | 65(61.32) | 64(42.11) | 0.002 |
More than one Retrieval Attempt | 43(40.57) | 87(57.24) | 0.008 |
TOAST classification, n (%) | |||
Large artery atherosclerosis | 63 (59.43) | 76(50.00) | 0.307 |
Cardioembolism | 41(38.68) | 72(47.37) | |
Others | 2(1.89) | 4(2.63) | |
Collateral circulation, n (%) | |||
2(1.89) | 19(12.50) | < 0.001 | |
13(12.26) | 37(24.34) | ||
67(63.21) | 83(54.61) | ||
24(22.64) | 13(8.55) | ||
Vascular occlusion site, n (%) | |||
ICA | 26(24.53) | 59(38.82) | 0.010 |
MCA | 69(65.09) | 70(46.05) | |
VA | 11(10.38) | 23(15.13) | |
Postoperative mTICI (≥ 2b) | 105(99.06) | 128(84.21) | < 0.001 |
Stroke-associated pneumonia | 29(27.36) | 108(71.05) | < 0.001 |
sICH, n (%) | 12(11.32) | 30(19.74) | 0.072 |
Laboratory data | |||
CRP(mmol/l) | 5.0(2.85–5.00) | 5.14(3.10–13.31) | 0.003 |
RDW(%) | 12.95 (12.50–13.40) | 13.00 (12.60–13.93) | 0.096 |
HGB(g/l) | 142.05 ± 19.37 | 131.86 ± 20.58 | < 0.001 |
GLU(mmol/l) | 6.71(6.01–8.09) | 8.35(6.70–10.21) | < 0.001 |
Na(mmol/L) | 140.15 ± 2.68 | 139.18 ± 3.32 | 0.014 |
Creatinine (μmol/L) | 68.65 (60.0–82.75) | 74.00 (61.00–92.00) | 0.064 |
BNP(ng/l) | 107.00 (22.25–270.50) | 234.00 (98.00–493.25) | < 0.001 |
Death | NA | ||
Vascular death | 0 | 43 | |
Recurrent ischemic stroke | 0 | 2 | |
Non-vascular death | 0 | 14 | |