From: Corneal confocal microscopy in the evaluation of immune-related motor neuron disease syndrome
Control (n = 10) | ALS (n = 33) | Immune-related MND syndrome (n = 39) | P | |
---|---|---|---|---|
Age | 43.8 ± 20.5 | 48.6 ± 11.1 | 55 ± 8.8 | 0.019*a |
Sex (male:female) | 4:6 | 24:9 | 18:21 | 0.076b |
Diagnostic delay (months) | - | 26.29 | 27 | 0.321 |
Site of onset (bulbar/limb) | - | 3:30 | 7:32 | 0.282 |
ALSFRS-R | - | 39.7 ± 5.4 | 40.2 ± 6.3 | 0.321 |
KCSS | - | 2 ± 0.9 | 1.9 ± 0.5 | 0.229 |
ΔFS | - | 0.7 ± 0.7 | 0.4 ± 0.4 | 0.205 |
LC density (cells/mm2)** | 21.8(17.1) | 45.8(54.1) | 104.1(81.2) | < 0.01*c |
IWL (mm/mm2) | 22.6 ± 4.6 | 16.4 ± 3.9 | 18.9 ± 4.7 | 0.001*d |