Risk factors of white matter hyperintensities in migraine patients

BMC Neurology

Table 3 Comparison of clinical characteristics between the non-WMH group and WMH group

Variable	Non-WMHs group (n = 36)	WMHs group (n = 24)	P value
Age	35.92+ 7.02	43.50 + 8.71	0.001*
Gender
• Male	• 5 (50)	• 5 (50)	0.480
• Female	•31 (62)	•19 (38)	0.480
Mean Disease Duration	8.58+ 6.49	14.54+ 7.76	0.002*
Mean Frequency of headache/month	4.11 + 6.48	7.96+ 5.53	0.020*
Mean duration of headache attach in hour	15.25+ 10.29	12.17+ 14.20	0.333
• Episodic Migraine	• 34 (65.4)	• 18 (34.6)	0.030*
• Chronic Migraine	• 2 (25)	• 6 (75)	0.030*
• Migraine with aura	• 2 (16.7)	• 10 (83.3)	0.001*
• Migraine without aura	• 34 (70.8)	• 14 (29.2)	0.001*
VAS	8.28+ 1.83	8.33 + 1.43	0.901
Mean HIT 6 score	60.81+ 9.64	69.25 + 9.02	0.001*
Mean MIDAS score	41.33+ 7.90	74.04 + 13.61	0.030*
Mean MOCA score	28.89 + 1.01	28.91+ 0.83	0.659
Mean Serum level of Homocysteine	7.78+ 2.41	9.27 + 4.31	0.006*

HIT-6 Headache Impact Test, MIDAS Migraine Disability Assessment Scale, MoCA Montreal Cognitive Assessment, NA not available, NC normal control, SD standard deviation, VAS visual analogue scale, WMHs White matter hyperintensities
*A significance level, P < 0.05

ISSN: 1471-2377