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Table 3 Immunological profile in blood and PBMC of stroke patients and controls

From: Stroke-derived neutrophils demonstrate higher formation potential and impaired resolution of CD66b + driven neutrophil extracellular traps

 

Stroke patients (n = 35)

Controls (n = 16)

 

Median (IQR)b

Median (IQR)

Ua, p value

granulocytes 103/μL

9.23 (5.88–20.73)

5.22 (3.97–7.33)

128, 0.007

CD66b + neutrophils 103/μL

2.44 (21.75–30.25)

2.03 (10.67–28.80)

n.s

DNAse-I U/L

17.03 (13.91–20.72)

12.24 (10.59–13.20)

24.5, <0.001

IL-17-producing CD4+ cells/μl

64.9 (26.6–397.0)

3.18 (2.40–13.70)

17, <0.001

IL-22-producing CD4+ cells/μl

265.1 (132.1–775.1)

6.10 (3.81–9.53)

25.5, <0.001

INF-γ-producing CD4+ cells/μl

632 (172.75–1242,62)

54.24 (30.88–98.30)

55, <0.001

CD4 cells/μl

2467 (841–4678)

712 (420–991)

94, 0.005

LDG 103/μL

1.93 (0.40–6.84)

0.24 (0.14–0.72)

116, 0.003

  1. aMann Whitney test U, bnon normal distribution