Fig. 1
From: Genetic origin of patients having spastic paraplegia with or without other neurologic manifestations
The brain MRIs of four cases. a case 14/SPG35, FLAIR sequences showed hyperintensities in the white matter (A-C) b case 22/X-ALD, FLAIR sequences demonstrated bilateral hyperintensities in the deep white matter, corpus callosum and internal capsules (D-F) c. case 25/Krabbe’s Disease, FLAIR sequences showed hyperintensities in the corticospinal tracts starting in the precentral gyrus and extending to corona radiata, posterior limb of internal capsules, as well as in the terminal areas of white matter (G-I) d. case 27/ARSACS, T2-FLAIR-sequences showed linear hypointensity in the pons and cerebellar atrophy (J-L)