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Table 2 The Hub genes related to PCD

From: Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer’s disease revealed by weighted gene co-expression network analysis

Gene

Full Name

DPI

Score

DNAI1

dynein axonemal intermediate chain 1

0.692

0.6

DNAAF3

dynein axonemal assembly factor 3

0.731

0.59

CCDC114

coiled-coil domain containing 114

0.5

0.53

CCDC65

coiled-coil domain containing 65

0.5

0.52

DNAH5

dynein axonemal heavy chain 5

0.692

0.4

RSPH1

radial spoke head component 1

0.5

0.36

CCDC39

coiled-coil domain containing 39

0.615

0.35

ZMYND10

zinc finger MYND-type containing 10

0.731

0.35

DNAI2

dynein axonemal intermediate chain 2

0.5

0.34

DNAAF1

dynein axonemal assembly factor 1

0.654

0.33

ARMC4

armadillo repeat containing 4

0.615

0.32

DRC1

dynein regulatory complex subunit 1

0.654

0.32

FOXJ1

forkhead box J1

0.577

0.32

HYDIN

HYDIN axonemal central pair apparatus protein

0.538

0.31

TTC25

tetratricopeptide repeat domain 25

0.538

0.31

TEKT1

tektin 1

0.308

0.01

  1. Data retrieved from the Disgenet database (https://www.disgenet.org/)
  2. PCD Primary Ciliary Dyskinesia
  3. DPI Disease Pleiotropy index for the gene
  4. Score: Gene-Disease Association Score