Table 6 Trend of the headache days by change in the number of the headache preventative medications
From: OnabotulinumtoxinA in chronic migraine: is the response dose dependent?
Number of the headache days | Number of the severe headache days | |
|---|---|---|
Patients who were on the same number of the preventative medications (n = 146) | ||
Baseline | 25.94 ± 5.77 | 15.54 ± 8.04 |
36 weeks before the increase | 13.55 ± 11.04 | 5.66 ± 6.97 |
24 weeks before the increase | 12.67 ± 10.78 | 5.19 ± 6.86 |
12 weeks before the increase | 13.04 ± 10.73 | 5.00 ± 6.46 |
Day of increase to 200 units | 12.81 ± 10.66 | 5.42 ± 6.26 |
12 weeks after the increase | 10.85 ± 10.36 ** | 3.77 ± 4.71 *** |
24 weeks after the increase | 11.70 ± 10.45 | 3.59 ± 4.73 *** |
36 weeks after the increase | 10.36 ± 10.46 ** | 3.70 ± 4.73 *** |
Patients who were on different number of the preventative medications (n = 29) | ||
Baseline | 25.41 ± 5.56 | 13.52 ± 7.44 |
36 weeks before the increase | 17.55 ± 9.02 | 7.00 ± 5.85 |
24 weeks before the increase | 18.17 ± 10.51 | 6.83 ± 6.08 |
12 weeks before the increase | 17.07 ± 9.89 | 6.90 ± 6.49 |
Day of increase to 200 units | 17.69 ± 10.69 | 8.21 ± 8.47 |
12 weeks after the increase | 17.07 ± 10.12 | 7.17 ± 6.74 |
24 weeks after the increase | 15.79 ± 11.42 | 5.00 ± 5.96 * |
36 weeks after the increase | 14.34 ± 10.92 * | 5.55 ± 5.43 * |