Table 3 Secondary outcomes
Self-reported outcome variable | Researcher | Participant | Moment of measurement (in addition to baseline) | Measurement unit |
|---|---|---|---|---|
General symptom impression | X | Directly after intervention and post-intervention 30 min, 1 h, 2 h, 3 h, 4 h and 5 h, and once every morning on the next three days | 10-point Likert scale allowing half points | |
Urge for dopaminergic medication on the usual moments of intake | X | Directly after intervention and post-intervention 30 min, 1 h, 2 h, 3 h, 4 h and 5 h, and once every morning on the next three days | 10-point Likert scale allowing half points | |
Participant-selected symptom (goal attainment scale) | X | Directly after intervention and post-intervention 30 min, 1 h, 2 h, 3 h, 4 h and 5 h, and once every morning on the next three days | 10-point Likert scale allowing half points | |
Motor symptom severity (self-selected, symptom that improved most during high altitude exposure, if applicable) | X | Directly after intervention and post-intervention 30 min, 1 h, 2 h, 3 h, 4 h and 5 h, and once every morning on the next three days | 10-point Likert scale allowing half points | |
Motor symptoms MDS-UPDRS part III | X | 30 min post-intervention | Total score and subscores | |
Hand tremor Accelerometry/gyroscope | X | Directly post-intervention, 30 min post-intervention | Amplitude | |
Rapid alternating movements Accelerometry/gyroscope | X | 30 min post-intervention | Amplitude | |
Bradykinesia Modified Perdue pegboard test | X | 30 min post-intervention | Number of pins | |
Gait Timed Up & Go Test | X | 30 min post-intervention | Steps and seconds | |
Balance MiniBESTest | X | 30 min post-intervention | Total score and subscores | |
Non-motor symptoms MDS Non-motor Scale symptoms | X | 30 min post-intervention | 10-point Likert scale (half points) | |
Stress Heartrate variability | X | During intervention, directly after intervention, 30 min post-intervention | RR interval |