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Table 2 Differences in cortical thickness and subcortical volume between individuals with glaucoma and their age, sex, and educational level-matched individuals without glaucoma

From: Reduced brain subcortical volumes in patients with glaucoma: a pilot neuroimaging study using the region-of-interest-based approach

 

Individuals with glaucoma (N = 64)

Individuals without glaucoma (N = 128)

pa

Mean ± standard deviation

Mean ± standard deviation

Cortical thickness (mm)

Global

2.41 ± 0.09

2.43 ± 0.09

0.16

 

Frontal lobe

2.46 ± 0.11

2.48 ± 0.11

0.39

 

Parietal lobe

2.16 ± 0.12

2.20 ± 0.11

0.051

 

Temporal lobe

2.70 ± 0.11

2.72 ± 0.12

0.17

 

Occipital lobe

1.88 ± 0.10

1.92 ± 0.09

0.005

 

Cingulate

2.45 ± 0.13

2.46 ± 0.14

0.58

 

Insula

2.84 ± 0.13

2.84 ± 0.16

0.86

Subcortical volume (mm3)

Thalamus

6057.84 ± 644.70

6360.02 ± 675.99

0.003

 

Caudate

3033.387 ± 447.86

3222.19 ± 510.70

0.013

 

Putamen

4123.42 ± 466.39

4251.56 ± 531.30

0.10

 

Pallidum

1729.90 ± 212.57

1817.86 ± 202.77

0.006

 

Hippocampus

3646.42 ± 402.72

3757.53 ± 360.48

0.054

 

Amygdala

1424.78 ± 196.56

1500.58 ± 207.17

0.016

 

Nucleus accumbens

363.53 ± 69.87

380.01 ± 78.60

0.16

  1. a Significance of difference between individuals with and without glaucoma; calculated by paired t-test