Characteristic | NMOSD(n = 86) |
---|---|
Female: male (ratio) | 75:11(7:1) |
Age, y, mean ± sd | 46.2 ± 13.8 |
AQP4-IgG-positive, n (%) | 74(86.0) |
History of myelitis during the disease, n (%) | 83(96.5) |
EDSS, mean ± sd | 4.3 ± 2.7 |
Length of spinal cord involvement, mean ± sda | 4.4 ± 4.7 |
Attack type, n (%) | |
Optic neuritis | 27(31.4) |
Myelitis | 63(73.3) |
Brain stem | 17(19.8) |
MR lesion type, n (%)a | |
Cervical | 30(44.8) |
Thoracic | 33(49.3) |
Lumber | 2(3.0) |
Brain stem | 18(26.9) |
Optic | 8(11.9) |
Isolated thoracic, n (%)a | 13(19.4) |
Upper thoracic lesions, n (%)a | 27(40.3) |
Lower thoracic lesions, n (%)a | 18(26.9) |
≥ 4 thoracic lesions, n (%)a | 18(26.9) |
≥ 3 spinal lesions, n (%)a | 40(59.7) |
IVMP, n (%) | 65(87.8) |
Intravenous immunoglobulin, n (%) | 16(21.6) |
Plasma exchange, n (%) | 2(2.7) |
Oral glucocorticoid, n (%) | 83(96.5) |
AZA, n (%) | 45(52.3) |
MMF, n (%) | 13(15.1) |