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Table 3 Retina angiography data of MOGAD-ON eyes in comparison to AQP4-Ab-ON eyes and health controls

From: The difference of the retinal structural and microvascular characteristics in patients with MOGAD-ON and AQP4-ON

 

MOG-ON

AQP4-ON

HC

MOG-ON VS. AQP4-ON

MOG-ON VS. HC

 

Eye = 26

Eye = 40

Eye = 60

B

SE

p

B

SE

p

Optic disk RPC (%)

49.53 (4.87)

49.14 (6.42)

55.35 (3.82)

−0.072

0.051

0.154

−0.288

0.069

0.000*

Capillary RPC (%)

52.74 (5.98)

48.63 (7.51)

51.14 (2.13)

−0.058

0.046

0.203

−0.808

0.194

0.000*

Superficial retina VD

 Whole VD (%)

44.22 (4.69)

46.01 (6.31)

51.99 (2.88)

−0.041

0.041

0.320

−0.560

0.122

0.000*

 Fovea (%)

13.16 (6.43)

15.31 (6.02)

19.91 (6.60)

−0.045

0.045

0.310

−0.168

0.452

0.000*

 para-TEM (%)

46.13 (5.55)

48.27 (6.56)

53.31 (3.38)

−0.029

0.039

0.462

−0.323

0.074

0.000*

 para-SUP (%)

47.93 (6.07)

49.26 (6.77)

54.53 (4.02)

−0.039

0.043

0.366

−0.263

0.065

0.000*

 para-NAS (%)

44.64 (6.16)

47.93 (6.57)

52.83 (3.86)

−0.090

0.044

0.040*

−0.315

0.073

0.000*

 para-INF (%)

45.22 (6.73)

47.87 (6.84)

53.43 (4.76)

−0.066

0.042

0.110

−0.231

0.054

0.000*

 peri-TEM (%)

42.54 (3.56)

44.30 (5.56)

48.40 (2.77)

−0.097

0.058

0.094

−0.498

0.103

0.000*

 peri-SUP (%)

45.01 (5.18)

46.54 (7.39)

53.09 (2.98)

−0.043

0.428

0.313

−0.511

0.116

0.000*

 peri-NAS (%)

46.73 (6.0)1

48.92 (6.83)

55.89 (2.77)

−0.059

0.436

0.173

−0.507

0.112

0.000*

 peri-INF (%)

44.41 (6.07)

46.27 (7.34)

52.53 (3.17)

−0.053

0.417

0.207

−0.402

0.091

0.000*

Deep retina VD

 Whole VD (%)

48.01 (7.58)

52.61 (6.72)

54.84 (5.41)

−0.091

0.040

0.022*

−0.163

0.045

0.000*

 Fovea (%)

29.28 (7.03)

31.99 (6.88)

37.12 (8.06)

−0.046

0.041

0.259

−0.123

0.036

0.001*

 para-TEM (%)

54.38 (8.16)

57.78 (4.84)

59.57 (3.72)

−0.086

0.050

0.087

−0.192

0.062

0.002*

 para-SUP (%)

53.75 (7.39)

57.73 (5.19)

58.25 (4.35)

−1.488

1.532

0.044*

−0.137

0.048

0.004*

 para-NAS (%)

53.75 (8.18)

57.64 (5.69)

59.47 (4.24)

−0.107

0.049

0.029*

−0.172

0.053

0.001*

 para-INF (%)

50.77 (8.44)

56.03 (5.98)

57.38 (5.32)

−0.101

0.042

0.016*

−0.142

0.042

0.001*

 peri-TEM (%)

51.52 (6.90)

54.68 (6.76)

57.86 (4.86)

−0.073

0.039

0.062

−0.197

0.052

0.000*

 peri-SUP (%)

48.12 (9.65)

53.18 (8.12)

56.40 (6.65)

−0.063

0.032

0.052

−0.129

0.038

0.001*

 peri-NAS (%)

47.18 (9.17)

54.19 (7.45)

55.01 (6.50)

−0.098

0.035

0.005*

−0.130

0.037

0.000*

 peri-INF (%)

47.58 (8.55)

52.86 (8.09)

55.21 (6.70)

−0.073

0.033

0.028*

−0.125

0.036

0.000*

  1. AQP4-ON Aquaporin4-IgG seropositive optical neuritis, B Beta, GCC Ganglion cell complex, HC Health controls, INF Inferior quadrant, MOGAD-ON MOG-Ab-associated disease optical neuritis, NAS Nasal quadrant, pRNFL peri-papillary retinal nerve fiber layer, RPC radial peripapillary capillaries,  SUP Superior quadrant, SE Standard error, TEM Temporal quadrant, VD Vessel densities, * p＜0.05
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BMC Neurology

ISSN: 1471-2377

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