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Fig. 2 | BMC Neurology

Fig. 2

From: RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization

Fig. 2

DNMT1 siRNA alleviated CCI-induced NP. CCI rats were treated with DNMT1 siRNA. A Expression of DNMT1 mRNA determined by RT-qPCR; B Protein level of DNMT1 determined by Western blot; C-D Measurement of MWT and TWL; E Levels of TNF-α, IL-1β, IL-6, and IL-10 determined using ELISA. N = 4, data were expressed as mean ± SD. The t-test was adopted to analyze the data in panels A/B/E and one-way repeated measures ANOVA was adopted to analyze the data in panels C/D. *p < 0.05, **p < 0.01, ***p < 0.001

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BMC Neurology

ISSN: 1471-2377

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