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Fig. 3 | BMC Neurology

Fig. 3

From: RNA interference-mediated silencing of DNA methyltransferase 1 attenuates neuropathic pain by accelerating microglia M2 polarization

Fig. 3

DNMT1 siRNA promoted microglia M2 polarization in CCI rats. A-D Expression and localization of iNOS and Arg-1 in microglia detected by immunofluorescence (red, Iba-1; green, iNOS and Arg-1); E Ratio of M1/M2 microglia; F-I Percentages of M1 microglia phenotype (CD16) and M2 microglia phenotype (CD206) detected using flow cytometry; J Ratio of M1/M2 microglia. N = 4, data were exhibited as mean ± SD. Data among multiple groups were analyzed by one-way ANOVA, followed by Tukey’s test. *p < 0.05, **p < 0.01, ***p < 0.001

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BMC Neurology

ISSN: 1471-2377

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