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Table 1 Clinical characteristics of patients with isolated API presenting with and without END

From: Risk factors for early neurological deterioration in acute isolated pontine infarction without any causative artery stenosis

 

END (n = 47)

Non-END (n = 106)

P

Age, mean ± SD, year

65.3 ± 11.9

68.1 ± 11.0

0.158

 Female, sex, n (%)

18 (38.3)

44 (41.5)

0.709

 Hypertension, n (%)

38 (80.9)

78 (73.6)

0.333

 Diabetes, n (%)

22 (46.8)

36 (34.0)

0.131

 Smoking, n (%)

12 (25.5)

20 (18.9)

0.350

 Drinking, n (%)

5 (10.6)

17 (16.0)

0.380

 History of ischemic stroke, n (%)

0 (0.0)

2 (1.9)

0.343

Blood pressure at admission

 SBP, mean ± SD, mmHg

151.5 ± 19.9

152.2 ± 24.3

0.87

 DBP, mean ± SD, mmHg

82.7 ± 12.3

85.5 ± 13.9

0.234

 Baseline blood glucose level, median (IQR), mmol/L

7.2 6.2, 11.2)

6.7 (5.5, 11.2)

0.260

 Arrival time, median (IQR), hours

20.0 (7.0, 24.0)

24.0 (10.0, 48.0)

0.085

 NIHSS score at admission, median, mean ± SD

3.9 ± 2.1

3.9 ± 2.6

0.992

 NIHSS score at discharge, median (IQR)

4.9 ± 2.5

2.4 ± 2.0

0.000

 Number of hospital days

13.2 ± 3.1

11.8 ± 3.0

0.007

Laboratory tests

 Total cholesterol, mmol/l, mean ± SD

4.7 ± 1.4

4.7 ± 1.3

0.958

 Triglycerides, mmol/l, median (IQR)

1.47 (1.05,2.12)

1.60 (1.05, 2.31)

0.826

 HDL, mmol/l, median (IQR)

1.11 (0.93, 1.26)

1.18 (1.01, 1.36)

0.062

 LDL, mmol/l, mean ± SD

2.9 ± 1.2

2.7 ± 1.0

0.490

 Creatinine, mmol/l, mean ± SD

66.6 ± 15.7

72.3 ± 23.3

0.08

 AST, mmol/l, median (IQR)

19.0 (15.0, 24.0)

19.0 (15.0, 25.0)

0.960

 ALT, mmol/l, median (IQR)

22.0 (17.0, 31.0)

20.0 (16.0, 27.2)

0.197

Treatment, n (%)

0.168

 IVT + DAPT

7 (14.9)

6 (5.7)

 

 DAPT

32 (68.1)

80 (75.5)

 

 Anticoagulation

8 (17.0)

20 (18.9)

 
  1. SD Standard deviation, SBP Systolic blood pressure, DBP Diastolic blood pressure, IQR Interquartile range, NIHSS National institutes of health stroke scale, HDL High-density lipoprotein, LDL Low-density lipoprotein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, IVT, Intravenous thrombolytic therapy, DAPT Dual antiplatelet therapy