Fig. 1

A Six patients with epilepsy, showing hyperperfusion of ASL in selective areas the cerebellar paravermis of lobule VIIb. Four patients (Patient 1, 3, 4, and 5) showed hypoperfusion of the VIIb lobule in short PLD conditions (1525 msec in Patient 1 and Patient 4, 1525 and 1800 msec in Patient 3, and 1800 msec in Patient 5) and showed hyperperfusion of the same region in longer PLD conditions. In Patient 4 and Patient 5 with focal epilepsy manifesting with asymmetrical motor symptoms, cerebellar hyperperfusion was found on the opposite side to the seizure focus estimated by seizure semiology. B Axial ASL images of Patient 1. At the bottom of the right cerebellum, hypoperfusion in PLD 1525 msec and hyperperfusion in PLD 1800 and 2500 msec are seen. In the left thalamus, hypoperfusion in PLD 1800 and 2500 msec is shown. C Co-registration of ASL to FLAIR images. ASL: arterial spin labeling, PLD: post labeling delay, FLAIR: fluid-attenuated inversion-recovery, M/F: male/female, EEG: electroencephalogram, R: right, L: left, Bil: bilateral, G: generalized, F: frontal, C: central, P: parietal, O: occipital, T: temporal, pT: posteriotemporal, PPR: photoparoxysmal response