The potential impact of insulin resistance and metabolic syndrome on migraine headache characteristics

BMC Neurology

Table 4 Correlations between duration and severity of migraine attacks and the laboratory markers of insulin resistance and metabolic syndrome

		Attack duration	MEGSEV	HIT	FBS	TGs	HDL	Insulin	HOMA-IR
Attack duration	(r) Coef.	1	0.333	0.366	0.148	0.077	-0.534	0.134	0.299
Attack duration	P-value	.	0.072	0.047*	0.434	0.686	0.002*	0.482	0.108
MEGSEV	(r) Coef.	0.333	1	0.705	0.437	0.302	-0.164	0.486	0.721
MEGSEV	P-value	0.072	.	< 0.001*	0.016*	0.104	0.387	0.006*	< 0.001*
HIT	(r) Coef.	0.366	0.705	1	0.325	0.295	-0.026	0.433	0.704
HIT	P-value	0.047*	< 0.001*	.	0.08	0.114	0.891	0.017*	< 0.001*
FBS	(r) Coef.	0.148	0.437	0.325	1	0.521	-0.282	0.358	0.390
FBS	P-value	0.434	0.016*	0.08	.	0.003*	0.131	0.052	0.033*
TGs	(r) Coef.	0.077	0.302	0.295	0.521	1	-0.213	0.268	0.317
TGs	P-value	0.686	0.104	0.114	0.003*	.	0.258	0.152	0.088
HDL	(r) Coef.	-0.534	-0.164	-0.026	-0.282	-0.213	1	0.111	0.071
HDL	P-value	0.002*	0.387	0.891	0.131	0.258	.	0.559	0.708
Insulin	(r) Coef.	0.134	0.486	0.433	0.358	0.268	0.111	1	0.813
Insulin	P-value	0.482	0.006*	0.017*	0.052	0.152	0.559	.	< 0.001*
HOMA-IR	(r) Coef.	0.299	0.721	0.704	0.390	0.317	0.071	0.813	1
HOMA-IR	P-value	0.108	< 0.001*	< 0.001*	0.033*	0.088	0.708	< 0.001*	.

FBS Fasting blood sugar, HDL High-density lipoprotein, HIT Headache Impact Test-6, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, MIGSEV Migraine Severity Scale, TGs Triglycerides
(r): Spearman coefficient, *P-value ≤ 0.05 is considered significant

ISSN: 1471-2377