The potential impact of insulin resistance and metabolic syndrome on migraine headache characteristics

BMC Neurology

Table 5 Multivariate regression analysis to detect the laboratory markers associated with increased duration and severity of migraine headache attacks

		Unstandardized Coefficients		Standardized Coefficients	t	P-value	95.0% Confidence Interval for B		Collinearity Statistics
		B	SE	Beta	t	P-value	Lower Bound	Upper Bound	Tolerance	VIF
Attack duration^a	Constant	31.395	12.232		2.567	0.017	6.150	56.640
	FBS	-0.073	0.112	-0.133	-0.651	0.521	-0.305	0.159	0.747	1.339
	TGs	-0.025	0.029	-0.187	-0.863	0.397	-0.086	0.035	0.665	1.505
	HDL	-0.267	0.122	-0.448	-2.182	0.039*	-0.519	-0.015	0.740	1.351
	Insulin	-0.833	0.788	-0.372	-1.057	0.301	-2.460	0.794	0.251	3.981
	HOMA-IR	5.356	2.904	0.627	1.844	0.078	-0.638	11.350	0.269	3.715
MEGSEV^b	Constant	0.297	1.087		0.273	0.787	-1.946	2.540
	FBS	0.016	0.010	0.225	1.567	0.130	-0.005	0.036	0.747	1.339
	TGs	-0.001	0.003	-0.081	-0.529	0.602	-0.007	0.004	0.665	1.505
	HDL	-0.009	0.011	-0.119	-0.828	0.416	-0.031	0.013	0.740	1.351
	Insulin	-0.106	0.070	-0.374	-1.511	0.144	-0.250	0.039	0.251	3.981
	HOMA-IR	1.083	0.258	1.005	4.197	<0.001*	0.550	1.615	0.269	3.715
HIT^c	Constant	32.816	15.281		2.148	0.042	1.278	64.354
	FBS	0.146	0.140	0.178	1.037	0.310	-0.144	0.435	0.747	1.339
	TGs	0.013	0.037	0.066	0.362	0.720	-0.062	0.089	0.665	1.505
	HDL	0.017	0.153	0.019	0.110	0.913	-0.299	0.332	0.740	1.351
	Insulin	-1.813	0.985	-0.544	-1.841	0.078	-3.846	0.219	0.251	3.981
	HOMA-IR	12.623	3.628	0.993	3.479	0.002*	5.134	20.111	0.269	3.715

FBS Fasting blood sugar, HDL High-density lipoprotein, HIT Headache Impact Test-6, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, MIGSEV Migraine Severity Scale, TGs Triglycerides.
^aAdjusted R square=0.097, ^bAdjusted R square= 0.553, ^cAdjusted R square= 0.364
*P-value ≤ 0.05 is considered significant

ISSN: 1471-2377