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Table 1 Baseline clinical characteristics of patients with favorable and unfavorable 3-month outcomes

From: Increased neutrophil-to-lymphocyte ratio is associated with unfavorable functional outcomes in acute pontine infarction

Variable

Favorable outcome (n = 178)

Unfavorable outcome (n = 78)

P

Age (years)

65.3 ± 11.0

69.9 ± 10.2

0.002

Male, n (%)

110 (61.8)

45 (57.7)

0.536

Hypertension, n (%)

141 (79.2)

66 (84.6)

0.312

Diabetes, n (%)

78 (43.8)

33 (42.3)

0.822

Atrial fibrillation, n (%)

4 (2.2)

4 (5.1)

0.223

Stroke history, n (%)

36 (20.2)

20 (25.6)

0.335

Smoker, n (%)

53 (29.8)

19 (24.4)

0.375

Alcohol user, n (%)

32 (18.0)

11 (14.1)

0.445

Etiological subtype, n (%)

 LAOD

39 (21.9)

20 (25.6)

0.903

 CE

6 (3.4)

3 (3.8)

 

 BABD

72 (40.4)

33 (42.3)

 

 SAD

35 (19.7)

13 (16.7)

 

 OE

26 (14.6)

9 (11.5)

 

NIHSS score

4 (3–6)

8 (7–10)

 < 0.001

Admission to blood sampling time (h)

16.4 (14.3–20.8)

18.0 (14.5–21.3)

0.472

SBP (mmHg)

151.9 ± 20.1

152.6 ± 21.4

0.796

DBP (mmHg)

87.9 ± 11.6

89.5 ± 10.1

0.286

Neutrophils (109/L)

4.1 ± 1.3

5.4 ± 2.0

 < 0.001

Lymphocytes (109/L)

1.8 ± 0.5

1.5 ± 0.5

 < 0.001

Platelets (109/L)

170.8 ± 45.9

186.0 ± 49.9

0.019

NLR

2.2 (1.7–2.9)

3.4 (2.6–4.7)

 < 0.001

PLR

94.2 (78.9–115.3)

125.5 (96.6–143.0)

 < 0.001

NLR (n,%)

  

 < 0.001

 Low tertile

74 (41.6)

11 (14.1)

 

 Middle tertile

71 (39.9)

16 (20.5)

 

 High tertile

33 (18.5)

51 (65.4)

 

PLR (n,%)

  

 < 0.001

 Low tertile

72 (40.4)

13 (16.7)

 

 Middle tertile

64 (36.0)

22 (28.2)

 

 High tertile

42 (23.6)

43 (55.1)

 

FBG (mmol/L)

5.6 (4.8–7.3)

5.8 (5.0–8.0)

0.078

TG (mmol/L)

1.8 (1.3–2.5)

1.8 (1.3–2.2)

0.993

LDL (mmol/L)

2.7 ± 0.8

3.0 ± 1.1

0.031

TC (mmol/L)

4.5 ± 1.0

4.6 ± 1.1

0.181

Scr (μmol/L)

67.0 (55.0–77.0)

64.5 (55.0–78.0)

0.647

BUN (mmol/L)

5.4 (4.4–6.6)

5.7 (4.6–7.4)

0.166

UA (mmol/L)

330.8 ± 88.4

313.4 ± 95.8

0.157

Infarct size (mm)

13.4 ± 4.9

14.5 ± 5.0

0.112

BA stenosis, n (%)

35 (19.7)

20 (25.6)

0.284

  1. Values are expressed as the mean ± standard deviation; median IQR Interquartile range; n (%), OR, Odds ratio; 95% CI 95% Confidence interval, LAOD Large artery occlusive disease, CE Embolism of cardiac origin, BABD Basilar artery branch disease, SAD Small artery disease, OE Other etiology, NIHSS National institutes of health stroke scale, SBP Systolic blood pressure, DBP Diastolic blood pressure, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, FBG Fasting blood glucose, TC Total cholesterol, TG Triglyceride, LDL Low-density lipoprotein cholesterol, Scr Serum creatinine, BUN Blood urea nitrogen, UA Uric acid, BA Basilar artery
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BMC Neurology

ISSN: 1471-2377

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