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Table 3 Results of sensitivity, specificity, PPV, and NPV in distinguishing MCI and ADD from NDS

From: Validation of a novel computerized cognitive function test for the rapid detection of mild cognitive impairment

Cut-off value

NDC vs MCI

NDC vs ADD

Sen

Spe

PPV

NPV

Sen

Spe

PPV

NPV

7 / 8

23.5

100

100

64.9

78.3

100

100

82.8

8 / 9

29.4

95.8

83.3

65.7

91.3

95.8

95.5

92.0

9 / 10

41.2

91.7

77.8

68.8

95.7

91.7

91.7

95.7

10 / 11

64.7

87.5

78.6

77.8

95.7

87.5

88.0

95.5

11 / 12

70.6

87.5

80.0

80.8

100

87.5

88.5

100

12 / 13

76.5

79.2

72.2

82.6

100

79.2

82.1

100

13 / 14

76.5

75.0

68.4

81.8

100

75.0

79.3

100

14 / 15

82.4

66.7

63.6

84.2

100

66.7

74.2

100

15 / 16

100

58.3

63.0

100

100

58.3

69.7

100

  1. Data are presented as percentages (%)
  2. NDC non-demented controls, ADD Alzheimer’s disease dementia, MCI mild cognitive impairment, Sen sensitivity, Spe specificity, PPV positive predictive value, NPV negative predictive value