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Table 1 Comparison of general clinical data between the CMB and no-CMB groups

From: Correlation of lipoprotein-associated phospholipase A2 and cerebral microbleeds in patients with acute ischaemic stroke

Variables

CMB group (n = 71)

No-CMB group (n = 171)

P value

Demographic data

 Age, years

69.5 ± 9.9

66.7 ± 9.2

0.036

 Sex, male (%)

48 (67.6)

110 (64.3)

0.626

 History of smoking (%)

26 (36.6)

61 (35.7)

0.889

 History of drinking (%)

24 (33.8)

52 (30.4)

0.605

 Hypertension (%)

54 (76.1)

104 (60.8)

0.023

 Diabetes mellitus (%)

27 (38.0)

42 (24.6)

0.035

 Coronary heart disease (%)

16 (22.5)

44 (25.7)

0.600

 History of stroke (%)

26 (36.6)

58 (33.9)

0.688

 Atrial fibrillation (%)

9 (12.7)

21 (12.3)

0.932

 Use of anticoagulants (%)

4 (5.6)

9 (5.3)

0.907

 Use of antithrombotics (%)

16 (22.5)

32 (18.7)

0.497

 Use of statins (%)

14 (19.7)

25 (14.6)

0.326

Clinical data

 Systolic blood pressure (mmHg)

146.4 ± 13.4

142.9 ± 13.1

0.066

 Diastolic blood pressure (mmHg)

87.9 ± 7.9

86.2 ± 8.4

0.144

 NIHSS score

7 (4, 10)

6 (3, 9)

0.063

 ASPECT score

7 (5, 8)

7 (6, 9)

0.175

 Fazekas score

3 (2, 4)

2 (1, 3)

0.001

Laboratory data

 Hs-CRP (mg/L)

2.83 (1.62, 4.42)

2.46 (1.48, 4.14)

0.525

 FPG (mmol/l)

5.69 (5.23, 6.77)

5.55 (5.0 6, 5.98)

0.242

 TG (mmol/L)

1.46 (0.78, 1.94)

1.31 (0.70, 1.67)

0.156

 TC (mmol/L)

4.34 ± 0.71

4.12 ± 0.84

0.041

 LDL-C (mmol/L)

2.64 ± 0.45

2.51 ± 0.46

0.047

 HDL (mmol/L)

1.20 ± 0.24

1.25 ± 0.25

0.214

 PT (s)

11.75 ± 1.07

11.89 ± 0.95

0.347

 APTT (s)

31.23 ± 3.32

30.55 ± 3.38

0.152

 INR

1.08 ± 0.12

1.07 ± 0.11

0.483

 FIB (g/L)

2.79 ± 0.80

2.75 ± 0.83

0.707

 Cr (umol/l)

76.43 ± 11.84

77.87 ± 17.98

0.465

 HCY (umol/l)

16.31 ± 3.68

14.34 ± 4.14

0.001

 Lp-PLA2 (ng/ml)

196.07 ± 35.36

176.96 ± 32.01

0.000

  1. Abbreviations: CMBs Cerebral microbleeds, hs-CRP High-sensitivity C-reactive protein, FPG Fasting plasma glucose, TG Triglycerides, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL High-density lipoprotein, PT Prothrombin time, APTT Activated partial thromboplastin time, INR International Normalized Ratio, FIB Fibrinogen, Cr Creatinine, HCY Homocysteine, Lp-PLA2 Lipoprotein associated phospholipase A2