Table 2 baseline comparison between mRS 2–6 and mRS 0–1 groups

Age, years (median [IQR])

37 [33, 42]

38 [35, 42]

37 [32, 42]

0.03

Male, n (%)

111 (16.06)

20 (12.99)

91 (16.95)

0.24

Admission NIHSS score, (median [IQR])

2 [0, 5]

8 [6, 10]

1 [0, 3]

< 0.001

Thrombolysis, n (%)

31 (4.49)

10 (6.49)

21 (3.91)

0.17

Hypertension, n (%)

324 (46.89)

74 (48.05)

250 (46.55)

0.74

Diabetes, n (%)

121 (17.51)

26 (16.88)

95 (17.69)

0.81

Dyslipidemia, n (%)

91 (13.17)

12 (7.79)

79 (14.71)

0.03

Atrial fibrillation, n (%)

11 (1.59)

6 (3.90)

5 (0.93)

0.03

Prior ischemic stroke, n (%)

74 (10.71)

20 (12.99)

54 (10.06)

0.3

Prior hemorrhagic stroke, n (%)

9 (1.30)

4 (2.60)

5 (0.93)

0.23

Coronary heart disease, n (%)

22 (3.18)

5 (3.25)

17 (3.17)

0.91

Smoking status, n (%)

0.02

  Never smoker

302 (43.70)

52 (33.77)

250 (46.55)

  Past smoker

22 (3.18)

5 (3.25)

17 (3.17)

  Current smoker

367 (53.11)

97 (62.99)

270 (50.28)

Alcoholic status, n (%)

0.44

  Never drinked

475 (68.74)

100 (64.94)

375 (69.83)

  Past drinked

11 (1.59)

2 (1.30)

9 (1.68)

  Current drinking

205 (29.67)

52 (33.77)

153 (28.49)

Prior antiplatelet agents, n (%)

52 (7.53)

14 (9.09)

38 (7.08)

0.40

Prior anticoagulation agents, n (%)

11 (1.59)

5 (3.25)

6 (1.12)

0.14

Systolic blood pressure, mmHg (median [IQR])

141.00 [129.00, 161.00]

149.00 [129.25, 170.00]

140.00 [129.00, 159.00]

0.01

Diastolic blood pressure, mmHg (median [IQR])

91.00 [81.00, 104.00]

96.00 [82.00, 109.50]

90.00 [81.00, 103.00]

0.01

Triglyceride, mmol/L (median [IQR])

1.42 [1.03, 2.04]

1.38 [1.06, 1.91]

1.43 [1.02, 2.09]

0.68

Cholesterol, mmol/L (median [IQR])

3.74 [3.03, 4.53]

3.94 [3.29, 4.55]

3.66 [3.02, 4.52]

0.09

High density lipoprotein, mmol/L (median [IQR])

0.99 [0.85, 1.16]

0.99 [0.86, 1.13]

1.00 [0.85, 1.17]

0.65

Low density lipoprotein, mmol/L (median [IQR])

2.18 [1.63, 2.90]

2.36 [1.81, 3.00]

2.13 [1.60, 2.87]

0.04

CRP, mg/L (median [IQR])

1.18 [0.49, 3.66]

2.17 [0.90, 7.14]

1.01 [0.43, 2.93]

< 0.001

NLR (median [IQR])

2.60 [1.91, 3.85]

3.38 [2.48, 5.24]

2.39 [1.84, 3.54]

< 0.001

Glucose, mmol/L (median [IQR])

5.50 [4.70, 6.90]

5.92 [5.00, 7.68]

5.46 [4.62, 6.71]

0.01

Pulmonary infection, n (%)

32 (4.63)

17 (11.04)

15 (2.79)

< 0.001

Urinary infection, n (%)

5 (0.72)

1 (0.65)

4 (0.74)

1

Infectious diarrhea, n (%)

5 (0.72)

2 (1.30)

3 (0.56)

0.68

Deep venous thrombosis, n (%)

20 (2.89)

7 (4.55)

13 (2.42)

0.27

Hemorrhagic transformation, n (%)

101 (14.62)

34 (22.08)

67 (12.48)

0.01

TOAST, n (%)

0.1

  LAA

314 (45.44)

80 (51.95)

234 (43.58)

  CE

46 (6.66)

14 (9.09)

32 (5.96)

  SAA

80 (11.58)

15 (9.74)

65 (12.10)

  Other

150 (21.71)

30 (19.48)

120 (22.35)

  Unknown

101 (14.62)

15 (9.74)

86 (16.01)