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Table 2 Given treatments and features of intensive care in the identified NORSE subgroups

From: Early clinical features of new-onset refractory status epilepticus (NORSE) in adults

 

All patients (n = 19)

FIRES (n = 6)

Viral encephalitis (n = 5)

Afebrile NORSE group (n = 8)

FIRES vs non-FIRES

Number of antiseizure medications

4 (4-8)

9 (8-9)

3 (3-4)

4 (4-5)

p = 0.001

Number of anesthetics

2 (1-3)

4 (2-4)

1 (1-2)

1 (1-2)

p = 0.002

Antimicrobial medication

16 (84%)

6 (100%)

5 (100%)

5 (62.5%)

NS

Immunotherapy

7 (37%)

5 (83%)

1 (20%)

1 (12.5%)

0.01

STESS

4 (3-4)

4 (4-4)

3 (3-4)

4 (4-5)

NS

CBI-score

4 (2-9)

9 (7-9)

2 (1-3)

4 (2-4)

p < 0.001

Days in tertiary hospital

29 (15-59)

96 (78-152)

17 (15-29)

21 (10-33)

p = 0.017

Days in intensive care unit

16 (10-48)

69 (56-135)

12 (10-17)

11 (7-17)

p = 0.012

Days in anesthesia

4 (2-28)

54 (34-125)

2 (2-3)

3 (2-6)

p = 0.007

  1. Footnote to Table 2. NS not significant, STESS status epilepticus severity score, CBI-score comlication burden index. Data presented as number (%) and median (interquartile range)