Table 1 Characteristics of participants based on ATN classification

N

50

39

147

40

CU

37(44.05)

13(15.48)

16(19.04)

18(21.43)

MCI

11(9.40)

6(5.13)

82(70.09)

18(15.38)

AD

2(2.67)

20(26.67)

49(65.33)

4(5.33)

Age (Mean ± SD, years)

74.53 ± 6.09

75.58 ± 5.23

74.66 ± 7.26

77.00 ± 7.46

0.232^a

Gender (F/M)

19/31

12/27

61/86

17/23

1.000^b

Education (Mean ± SD, years)

15.28 ± 3.01

15.51 ± 3.50

15.83 ± 2.93

16.10 ± 2.62

0.514^a

APOE ε4 (n, %)

3 (6.00)

20 (51.28)

102 (69.39)

7 (17.50)

< 0.001^b

MMSE score

28.44 ± 1.47

26.51 ± 2.45

25.69 ± 3.31

28.20 ± 1.74

< 0.001^a

Aβ₄₂ (pg/ml)

1441.64 ± 252.09

639.87 ± 194.49

587.76 ± 176.21

1794.03 ± 664.20

< 0.001^a

t-tau (pg/ml)

191.10 ± 31.10

181.61 ± 33.97

353.71 ± 97.99

320.71 ± 81.04

< 0.001^a

p-tau (pg/ml)

16.78 ± 2.87

16.66 ± 3.53

35.99 ± 10.63

29.09 ± 9.66

< 0.001^a

Clusterin

20.56 ± 0.45

20.24 ± 0.45

20.38 ± 2.02

20.98 ± 0.36

< 0.001^a