Fig. 1

Cytokine levels at 72 h after onset in seven patients based on syndrome. The dotted line in the figure represents the reference value obtained from the control subjects with developmental delay (IL-1β, 1.4; IL-1RA, 228; IL-4, 1.4; IL-5, 6.2; IL-6, 3.3; IL-8, 6.0; IL-10, 1.6; IL-17, 13.5; eotaxin, 42.5; FGF, 34.2; GCSF, 20.0; IFN-γ, 6.8; IP-10, 427; MCP-1, 22.3; MIP-1α 1.6; and PDGF-bb, 2577). The cytokine levels in hemorrhagic shock and encephalopathy syndrome are marked as blue diamonds, acute encephalopathy with biphasic seizure and late reduced diffusion are marked as orange squares, and those in febrile seizure are marked as gray circles. The control data are expressed as average. Abbreviations: IL, interleukin; RA, receptor agonist; FGF, fibroblast growth factor; GCSF, granulocyte colony-stimulating factor; IFN-γ, interferon gamma; IP-10, interferon-inducible protein-10; MCP-1, monocyte chemoattractant protein-1; MIP-1α, macrophage inflammatory protein-1α; PDFG-bb, platelet-derived growth factor-bb