Skip to main content

Table 1 Univariate analysis of clinical characteristics related to HE in patients with ICH

From: A high neutrophil-to-platelet ratio is associated with hematoma expansion in patients with spontaneous intracerebral hemorrhage: a retrospective study

Characteristic

Total

(n = 317)

HE

(n =89)

No HE

(n =228)

p-Value

Age(years)

56(45,67.50)

58(49,70)

54(43,66)

0.028*

Sex (male)

230(72.6%)

61(68.5%)

169(74.1%)

0.329

Hypertension

258(81.4%)

76(85.4%)

182(79.8%)

0.335

Diabetes mellitus

26(8.2%)

6(6.7%)

20(8.8%)

0.653

Prior ischemic stroke

10(3.2%)

2(2.2%)

8(3.5%)

0.826

Prior ICH

11(3.5%)

4(4.5%)

7(3.1%)

0.779

Smoking

98(30.9%)

23(25.8%)

75(32.9%)

0.279

Alcohol consumption

83(26.2%)

19(21.3%)

64(28.1%)

0.256

Onset-to-first-CT time(hours)

7(4,15)

8(5,14.5)

7(4,15)

0.249

SBP(mmHg)

163 ± 27

162 ± 26

164 ± 27

0.664

DBP(mmHg)

96 ± 18

96 ± 16

97 ± 19

0.578

GCS score on admission

-

-

-

< 0.001**

13-15

114(36.0%)

15(16.9%)

99(43.4%)

-

9-12

104(32.8%)

29(32.6%)

75(32.9%)

-

3-8

99(31.2%)

45(50.6%)

54(23.7%)

-

NIHSS on admission

12(9,14)

12(10,14)

10(9,13)

0.019*

Infratentorial hematoma

67(21.1%)

20(22.5%)

47(20.6%)

0.760

Hematoma size (ml)

24.00(10.15,41.84)

35.24(14.98,52.20)

21.23(8.36,38.18)

<0.001**

Presence of IVH

133(42.0%)

42(47.2%)

91(39.9%)

0.256

RBC, x1012

4.58 ± 0.72

4.44 ± 0.75

4.63 ± 0.70

0.031*

Hemoglobin(g/L)

139 ± 20

135 ± 21

140 ± 19

0.061

Neutrophil, x109

8.12(5.25,11.33)

10.86(8.56,13.74)

6.85(4.74,9.93)

<0.001**

Lymphocyte, x109

1.22(0.79,1.83)

0.91(0.65,1.29)

1.31(0.87,1.93)

<0.001**

Monocyte, x109

0.51(0.38,0.73)

0.63(0.40,0.81)

0.50(0.35,0.69)

0.003*

Platelet, x109

185 ± 64

159 ± 60

195 ± 62

<0.001**

NPR

4.79(2.70,6.63)

7.37(5.46,9.67)

3.85(2.50,5.40)

<0.001**

PT (s)

10.9(10.5,11.4)

11.1(10.7,11.5)

10.9(10.4,11.3)

0.009*

APTT (s)

26.1(24.4,27.6)

25.4(24.2,27.6)

26.3(24.6,27.6)

0.224

INR

0.93(0.89,0.97)

0.95(0.91,1.00)

0.92(0.89,0.97)

0.005*

Blood glucose (mmol/L)

7.85(6.37,9.69)

8.68(7.08,11.87)

7.60(6.31,9.23)

<0.001**

  1. Values are n (%) and median (25,75%)
  2. HE hematoma expansion, ICH intracerebral hemorrhage, SBP systolic blood pressure, DBP diastolic blood pressure, GCS Glasgow coma scale, NIHSS National Institutes of Health stroke scale, IVH intraventricular hemorrhage, RBC red blood cells, NPR neutrophil to platelet ratio, PT prothrombin time, APTT activated partial thromboplastin time, INR international normalized ratio
  3. *p < 0.05. **p < 0.001