Table 1 Demographic and clinical characteristics

Age of onset (years)

Mean ± SD

14–77 (53.20 ± 11.29)

47–73 (60.08 ± 4.78)

32.5–75 (59.82 ± 10.28)

<0.001^a

0.862^b

Age of first treatment (years)

Mean ± SD

29–78 (58.00 ± 10.58)

51–78 (64.53 ± 4.36)

33–80 (64.89 ± 10.92)

<0.001^a

0.816^b

 Male

34

35

46

0.429^c

 Female

14

23

20

 Han

46

57

64

0.749^e

 Others

2

1

2

Family history

2

4

3

0.787^e

Smoking history

9

15

29

0.010^c/0.005^cd

Drinking history

10

4

9

0.105^e

Hypertension

17

20

27

0.727^c

Diabetes

9

15

18

0.551^c

Hyperlipidemia

10

11

14

0.948^c

History of head injury

3

5

6

0.849^e

History of carbon monoxide poisoning

6

5

11

0.407^c

Duration of disease (years)

Mean ± SD

0.5-20 (4.80 ± 4.38)

0.5-20 (4.46 ± 4.14)

0.5-30 (5.08 ± 5.19)

0.763^a