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Table 3 Comparison of total, baseline and new or aggravated clinical symptoms between L-CI and N-CI

From: Transcranial sonography with clinical and demographic characteristics to predict cognitive impairment in PD: a longitudinal study

Clinical symptoms

L-CI (n = 66)

N-CI (n = 48)

P1

L-CI t/n (n = 66)

N-CI t/n (n = 48)

P2

P3

MS

 Bradykinesia

66

48

NA

66/11

48/10

NA

0.571c

 Rest tremor

57

41

0.886c

58/7

43/9

0.777c

0.123c

 Rigidity

35

31

0.217c

37/8

34/10

0.108c

0.208c

Mental symptoms

 Memory deficit

30

18

0.396c

55/28

26/10

0.001c

0.016c

 RCP

9

3

0.337e

22/13

7/4

0.023c

0.157c

 Cognitive impairment

0

0

NA

66/0

0/0

NA

NA

 Somnipathy

10

7

0.933c

23/13

16/9

0.866c

0.899c

 Anxiety

28

13

0.092c

33/7

22/9

0.660c

0.123c

 Depression

27

9

0.012c

35/10

17/9

0.062c

0.611c

 Apathy

4

2

0.982e

5/1

2/0

0.724e

NA

Autonomic symptoms

 Constipation

45

26

0.127c

54/15

35/9

0.257c

0.607c

 Hyperhidrosis

0

1

NA

1/1

2/1

0.779e

NA*

 Postural hypotension

13

6

0.309c

25/13

17/11

0.788c

0.677c

 Dysuria

34

23

0.704c

44/11

34/11

0.637c

0.404c

 Salivation

11

4

0.308e

16/5

8/4

0.327c

NA*

 Sexual dysfunction

4

9

0.071e

6/2

10/1

0.075c

NA

Sensory disturbance

 Olfactory dysfunction

16

20

0.048c

27/11

26/6

0.161c

0.537c

 Pain

11

8

NA*

16/6

11/5

0.896c

0.813c

 Spasm

0

1

NA

0/0

1/0

NA

NA

 Numbness

3

2

NA*

4/2

2/0

0.982e

NA

 RLS

3

1

0.849e

3/0

1/0

0.873e

NA

  1. P1: Comparison of MS and NMS between L-CI and N-CI at the first treatment
  2. P2: Comparison of total clinical symptoms at the last treatment between L-CI and N-CI
  3. P3: Comparison of newly increased or aggravated clinical symptoms between L-CI and N-CI at the last treatment
  4. t/n total/ new or aggravated
  5. cChi square test
  6. eContinuity correction of chi square test