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Table 2 Univariate analysis between the unruptured and ruptured groups in the training and test groups

From: Rupture discrimination of multiple small (< 7 mm) intracranial aneurysms based on machine learning-based cluster analysis

 

Training group (n = 1010)

Test group (n = 417)

Unruptured

Ruptured

P-value

Unruptured

Ruptured

P-value

N (%)

894(88.5)

116(11.5)

 

368(88.2)

49 (11.8)

 

Cluster groups (%)

  

 < 0.001

  

 < 0.001

 Cluster 1

51(5.7)

33(28.4)

 

24(6.5%)

14(28.6)

 

 Cluster 2

159(17.8)

32(27.6)

 

50(13.6)

12(24.5)

 

 Cluster 3

684(76.5)

51(44.0)

 

294(79.9)

23(46.9)

 

Aneurysm-level characteristics

Size (mean ± SD)

3.9 ± 1.3

4.7 ± 1.3

 < 0.001

4.0 ± 1.4

4.9 ± 1.3

 < 0.001

Size Group (%)

  

0.012

  

0.006

  < 3

291(27.3)

14(13.5)

 

96(26.1)

4(8.2)

 

 3–7

573(53.7)

65(62.5)

 

272(73.9)

45(91.8)

 

Neck (mean ± SD)

3.2 ± 1.1

3.5 ± 1.1

0.004

3.3 ± 1.1

3.5 ± 1.2

0.012

AR (mean ± SD)

1.1 ± 0.4

1.3 ± 0.5

 < 0.001

1.1 ± 0.4

1.4 ± 0.5

 < 0.001

BPR (mean ± SD)

1.1 ± 0.3

1.0 ± 0.4

0.001

1.1 ± 0.3

1.0 ± 0.4

0.023

NPR (mean ± SD)

1.0 ± 0.4

1.1 ± 0.5

0.002

1.0 ± 0.4

1.1 ± 0.4

0.055

SR (mean ± SD)

1.0 ± 0.5

1.4 ± 0.6

 < 0.001

1.1 ± 0.5

1.5 ± 0.6

0.004

Location of PC (%)

66(7.4)

13(11.2)

0.149

29(7.9)

7(14.3)

0.134

Irregular shape (%)

259(29.0)

43(37.1)

0.073

89(24.2)

25(51.0)

 < 0.001

Bifurcation aneurysm (%)

190(21.3)

37(31.9)

0.010

84(22.8)

17(34.0)

0.083

Inflow angle (mean ± SD)

95 ± 33

103 ± 32

0.008

98 ± 35

110 ± 35

0.022

Outflow angle (mean ± SD)

101 ± 30

103 ± 29

0.612

99 ± 32

102 ± 34

0.538

Main branching angle (mean ± SD)

139 ± 33

134 ± 33

0.086

137 ± 34

131 ± 37

0.239

  1. SAH Subarachnoid hemorrhage, AR Aspect ratio, BPR Branching-to-parent ratio, NPR Neck-to-parent ratio, PC Posterior circulation