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Table 1 The comprassion of the basal demographic and laboratory findings and MLR, PLR, NLR, SII values of patient and control groups

From: The role of systemic ımmune ınflammatory ındex in showing active lesion ın patients with multiple sclerosis

 

Patient Group

Control Group(n = 94)

p

Total(n = 186)

Active Lesion( +)(n = 99)

Active Lesion(-)(n = 87)

Age(year) (mean ± SD)

33.21 ± 7.6

33.85 ± 9.6

32.72 ± 7.38

33.44 ± 8.04

b0.656

Gender(female(n,%))

141(75.8%)

73 (73.7%)

68 (78.2%)

65 (69.1)

c0.392

Disease Duration(year)(mean ± SD)

5.05 ± 4.65

-

-

-

EDSS(mean ± SD)

1.11 ± 0.49

-

-

-

Lesion count

 

1–5: 54 (54.5%)

6–10: 16(16.2%)

 ≥ 11: 29 (29,3%)

   

Lesion localisation

-

Supratentorial:77(77.8%)

Infratentorial:17(17.2%)

Spinal:5(5.1%)

-

-

CRP(mg/dL)

(median(min–max))

2.3 (0.1–9.8)

2.1 (0.1–9.8)

2.4 (0.1–8.5)

2.4(1–7.1)

b0.425

Monocyte count(109/L) (mean ± SD)

0.42 ± 0.19

0.50 ± 0.23

0.42 ± 0.17

0.34 ± 0.10

b 0.001**

Lymphocyte count(109/L) (median(min–max))

2.2 (0.9–4)

1.8 (0.9–2.9)

2.2 (0.9–3.5)

2.6 (1.4–4)

a 0.001**

Platelet count(109/L)

(mean ± SD)

281.11 ± 69.06

330.72 ± 63.74

285.92 ± 54.99

224.41 ± 36.62

b0.001**

Eosinophil count(109/L) (median(min–max))

0.1 (0–0.4)

0.1 (0–0.4)

0.1 (0–0.4)

0.1 (0–0.2)

a0.104

Neutrophil count(109/L) (median(min–max))

3.6 (1–14)

4.2 (2.1–14)

3.6 (1–14)

3.1 (1–4.9)

a 0.001**

MLR(median(min–max))

0.2 (0–1.3)

0.3 (0.1–1.3)

0.2 (0–0.7)

0.1 (0–0.3)

a0.001**

PLR(median(min–max))

122.8 (43.2–421.8)

189.8 (83.8–421.8)

135 (61.3–351.3)

89.3 (43.2–189)

a0.001**

NLR(median(min–max))

1.5 (0.4–10.6)

2.5 (1–10.6)

1.5 (0.5–10.6)

1.2 (0.4–2.8)

a0.001**

SII(median(min–max))

452.7 (71.1–3215.6)

797.9 (273–3215.6)

478.1 (151.9–3215.6)

234.2 (71.1–674)

a0.001**

  1. EDSS Expanded Disability Status Scale, CRP C- Reactive protein, MLR Monocyte/ lymphocyte ratio, PLR Platelet/ lymphocyte ratio, NLR Neutrophil / lymphocyte ratio, SII Systemic immune-inflammatory index
  2. aKruskal Wallis Test; bOne Way Anova Test; CFisher Freeman Halton Test All values are presented mean ± standard deviation(SD) or median value (min–max); **p<0.05