Table 3 Comparison between Mild, moderate and severe relapses; full recovered and unrecovered relapses regarding different numerical parameters
From: Predictors of severity and outcome of multiple sclerosis relapses
|  | Mild + Moderate Relapses (n = 183) | Severe relapses (n = 117) |  | Full or almost full recovery (n = 204) | Partial or no recovery (n = 96) |  | ||||
|---|---|---|---|---|---|---|---|---|---|---|
Mean ± Sd | Median(IQR) | Mean ± Sd | Median(IQR) | P value | Mean ± Sd | Median(IQR) | Mean ± Sd | Median(IQR) | P value | |
Age at disease onset | 26.8 ± 6.2 |  | 27.9 ± 7.1 |  | 0.17 | 26.72 ± 6.028 |  | 29.52 ± 7.31 |  | 0.0002 |
Age at onset of attack | 28.5 ± 6.7 |  | 29.1 ± 7.3 |  | 0.4 | 27.064 ± 6.22 |  | 32.479 ± 7.1 |  |  <  0.0001 |
EDSS before the onset |  | 0 (0—1.5) |  | 0 (0 – 0) | 0.0005 |  | 0 (0–0) |  | 1(0 – 2) |  <  0.0001 |
EDSS after the onset |  | 3 ( 3–4) |  | 4(3.5 – 4.5) |  <  0.0001 |  | 3(2.5 – 3.5) |  | 4 (3.5 – 4.5) |  <  0.0001 |
Time to maximum worsening (Zenith level)(days) |  | 1(1 -2) |  | 2(1 – 3) |  <  0.0001 |  | 1(1–2) |  | 2(1–3) | 0.005 |
EDSS at the Zenith Level |  | 3 (2.5 – 3) |  | 4.5 (3.5 – 6) |  <  0.0001 |  | 3.5 (3 – 4) |  | 4 (3.5—6) |  <  0.0001 |
Time to maximum improvement / Duration of the attack (days) |  | 30(25- 45) |  | 50(35 – 60) |  <  0.0001 |  | 30(25–50) |  | 50(40–60) |  <  0.0001 |
EDSS after recovery |  | 1 (1- 2) |  | 2 (1.5 – 2.5) |  <  0.0001 |  | 1 (1 – 2) |  | 2.5 (2 – 3) |  <  0.0001 |
Total number of relapses |  | 3(2–4) |  | 2 (1 -3) | 0.005 |  | 2(1–3) |  | 3(2–4) |  <  0.0001 |
Duration of disease prior to the attack (months) |  | 6 (0–30.5) |  | 0 (0–10) | 0.07 |  | 0(0–7) |  | 16(0–60) |  <  0.0001 |