From: Predictors of severity and outcome of multiple sclerosis relapses
Variable | Odds ratio | 95% CI | P | Relative risk | 95% CI | P value | NNT a | 95% CI |
---|---|---|---|---|---|---|---|---|
Presence of black holes in brain MRI | 5.425 | 1.401 to 21.008 | 0.014 | 3.825 | 2.343 – 6.242 |  <  0.0001 | 3.611 (Harm) | 5.325(Harm) -2.731 (Harm) |
Duration of Attack | 1.04 | 1.015 to 1.077 | 0.003 | Â | Â | Â | Â | Â |
Duration of Disease before the attack | 1.030 | 1.005 to 1.055 | 0.016 | Â | Â | Â | Â | Â |
EDSS after onset | 1.532 | 1.054 to 2.227 | 0.025 | Â | Â | Â | Â | Â |
Age at onset of disease | 1.1774 | 1.104 to 1.254 |  <  0.0001 |  |  |  |  |  |
Presence of smoking | 4.0007 | 1.583 to 10.107 | 0.0034 | 1.835 | 1.28—2.63 | 0.0009 | 5.551 (Harm) | 13.518(Harm) to 3.493 (Harm) |
Total Number of relapses | 3.0493 | 2.09 to 4.429 |  <  0.0001 |  |  |  |  |  |