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Table 2 Factors associated with long-term stented-territory infarction in VBS

From: In-stent restenosis and stented-territory infarction after carotid and vertebrobasilar artery stenting

Variable (N = 87)

cHR (95% CI)

P-value

aHR (95% CI)

P-value

Age

1.02 (0.97–1.07)

0.544

  

Male sex

1.50 (0.34–6.70)

0.597

  

Hypertension

1.40 (0.39–5.02)

0.606

  

Diabetes

3.17 (1.09–9.18)

0.034

3.82 (1.24–11.7)

0.019

Hyperlipidemia

0.40 (0.13–1.28)

0.122

  

Coronary artery disease

1.91 (0.60–6.09)

0.276

  

Stroke history

1.51 (0.53–4.32)

0.438

  

HbA1c, %

1.48 (0.96–2.28)

0.075

  

LDL, mg/dL

1.00 (0.99–1.01)

0.743

  

ARU ≥550

1.33 (0.40–4.43)

0.640

  

PRU ≥275

2.03 (0.45–9.15)

0.359

  

% PI < 20%

2.23 (0.72–6.90)

0.166

  

Intracranial lesion

1.47 (0.49–4.39)

0.491

  

Symptomatic stenosis

1.28 (0.17–9.81)

0.810

  

Number of stents ≥2

11.6 (1.42–94.0)

0.022

22.4 (2.4–206.4)

0.006

Maximum diameter of stents, mm

0.88 (0.64–1.22)

0.445

  

Total length of stents, mm

1.01 (0.96–1.07)

0.676

  

Pre-ballooning dilatation

2.36 (0.31–18.0)

0.409

  

Post-ballooning dilatation

0.78 (0.22–2.82)

0.708

  

Maximum balloon pressure, atm

0.94 (0.81–1.09)

0.388

  

In-stent restenosis

2.37 (0.65–8.64)

0.193

  
  1. aHR and P-value represent the results of multivariable cox proportional analysis. Variables with potential association (P < 0.10) were entered to the multivariable cox proportional analysis. Six patients who occurred periprocedural ischemic event were excluded in this analysis
  2. VBS Vertebrobasilar artery stenting, cHR Crude hazard ratio, aHR Adjusted hazard ratio, HbA1c Hemoglobin A1c, LDL Low-density lipoprotein, ARU Aspirin reaction unit, PRU P2Y12 reaction unit, % PI Percent platelet inhibition