Table 1 Baseline patient characteristics, cumulative steroid doses and time from first operation to recurrence or death (or time to last follow-up if still alive or recurrence-free)

Pat

Degree of completion (reason for withdrawal)

Age

Sex

MGMT status

WHO/ECOG performance status

MMSE score

Preoperative tumor volume (ml)

#1

Full

57

M

Unmethylated

1

29

9.2

#2

21/56 days (pulmonary embolism)

55

M

Unmethylated

1

28

45.7

#3

22/56 days (nausea)

62

M

Unmethylated

1

28

30.6

#4

Full

59

M

Unmethylated

1

28

40.5

#5

Full

51

M

Methylated

1

27

48.4

#6

Full

58

M

Unmethylated

1

28

30.2

#7

Full

54

M

Methylated

1

29

2.7

#8

Full

59

M

Unmethylated

0

28

6.7

Pat

Gross total resection on postoperative MRI

Residual tumor on postoperative MRI (ml)

Steroids at baseline? (dose, mg)

Cumulative betamethasone during trial (mg)

Repeat surgery? (months from primary op)

Cycles of adjuvant TMZ

#1

N

0.55

N (0)

5

N

0

#2

Y

0

Y (2)

23

Y (13.1)

6

#3

Y

0

N (1.5)

14

Y (8)

5

#4

N

7.3

Y (2)

143

N

5

#5

N

0.1

Y (2)

117

N

6

#6

N

11.5

N (1)

135

Y (8.7)

5

#7

Y

0

N (0)

96

Y (21.2)

6

#8

N

0.6

N (0)

77

Y (20.7)

6

Pat

Tumor treating fields?

Overall survival (months)

Progression free survival (months)

#1

N

12.4

4.3

#2

Y

22.3

12.6

#3

N

24.9

7.6

#4

N

11.3

6.5

#5

N

26^a

26^a

#6

Y

13.8

7.8

#7

Y

24^a

20.3

#8

Y

23.6

18.6