Table 1 Baseline characteristics of included patients grouped by HT or PH
Variables | Total (n=427) | HT | PH | ||||
|---|---|---|---|---|---|---|---|
Yes (n=56) | No (n=371) | P value | Yes (n=28) | No (n=399) | P value | ||
Sex, male | 256 (60.0) | 29 (51.8) | 227 (61.2) | 0.181 | 16 (57.1) | 240 (60.2) | 0.754 |
Age, years | 67.35±13.85 | 70.20±13.17 | 66.92±13.91 | 0.099 | 70.89±11.73 | 67.10±13.96 | 0.112 |
Systolic BP on admission, mmHg | 147.71±23.94 | 145.75±23.25 | 148.01±24.06 | 0.512 | 147.89±23.38 | 147.70±24.01 | 0.967 |
Diastolic BP on admission, mmHg | 85.47±14.94 | 87.50±17.95 | 85.16±14.44 | 0.355 | 90.39±19.54 | 85.12±14.54 | 0.071 |
NIHSS on admission | 6.0 (3.0-13.0) | 11.5 (8.0-15.8) | 5.0 (2.0-12.0) | <0.001 | 12.0 (8.3-14.8) | 5.0 (2.0-12.0) | <0.001 |
Vascular risk factors | |||||||
Hypertension | 247 (57.8) | 37 (66.1) | 210 (56.6) | 0.181 | 19 (67.9) | 228 (57.1) | 0.267 |
Diabetes mellitus | 88 (20.6) | 12 (21.4) | 76 (20.5) | 0.871 | 6 (21.4) | 82 (20.6) | 0.912 |
Hyperlipidemia | 17 (4.0) | 1 (1.8) | 16(4.3) | 0.711 | 0 (0.0) | 17(4.3) | 0.617 |
Atrial fibrillation | 74 (17.3) | 20 (35.7) | 54 (14.6) | <0.001 | 11 (39.3) | 63 (15.8) | 0.004 |
Current smoking | 160 (37.5) | 20 (35.7) | 140 (37.7) | 0.771 | 11 (39.3) | 149 (37.3) | 0.837 |
Alcohol consumption | 103 (24.1) | 11 (19.6) | 92 (24.8) | 0.401 | 9 (32.1) | 94 (23.6) | 0.305 |
Previous history of cardiovascular events | |||||||
Myocardial infarction | 11 (2.6) | 0 (0.0) | 11 (3.0) | 0.373 | 0 (0.0) | 11 (2.8) | 1.000 |
Transient ischemic attack | 9 (2.1) | 0 (0.0) | 9 (2.4) | 0.614 | 0 (0.0) | 9 (2.3) | 1.000 |
Previous ischemic stroke | 71 (16.6) | 9 (16.1) | 62 (16.7) | 0.905 | 5 (17.9) | 66 (16.5) | 0.796 |
Previous hemorrhagic stroke | 6 (1.4) | 0 (0.0) | 6 (1.6) | 1.000 | 0 (0.0) | 6 (1.5) | 1.000 |
TOAST classification of stroke etiology | <0.001 | 0.003 | |||||
Large-artery atherosclerosis | 128 (30.0) | 16(28.6) | 112(30.2) | 9(32.1) | 119(29.8) | ||
Small-vessel occlusion | 104 (24.4) | 1(1.8) | 103(27.8) | 0(0.0) | 104(26.1) | ||
Cardioembolism | 116 (27.2) | 26(46.4) | 90(24.3) | 13(46.4) | 103(25.8) | ||
Other cause | 12 (2.8) | 1(1.8) | 11(3.0) | 1(3.6) | 11(2.8) | ||
Undetermined etiology Stroke | 67 (15.7) | 12(21.4) | 55(14.8) | 5(17.9) | 62(15.5) | ||
Homocysteine, umol/L | 13.5(10.9-16.8) | 15.0(11.5-17.9) | 13.3(10.8-16.6) | 0.048 | 16.5(12.5-21.1) | 13.3(10.8-16.4) | 0.008 |
Glucose on admission, mmol/L | 7.97±3.36 | 7.96±2.09 | 7.97±3.51 | 0.986 | 8.26±2.40 | 7.95±3.42 | 0.635 |
Blood creatine on admission, μmol/L | 80.36±42.42 | 79.81±37.36 | 80.44±43.18 | 0.917 | 84.15±43.01 | 80.09±42.42 | 0.625 |
Therapies after stroke onset | |||||||
Thrombolysis | 44 (10.3) | 9 (16.1) | 35 (9.4) | 0.154 | 3 (10.7) | 41(10.3) | 1.000 |
Thrombectomy | 20 (4.7) | 5 (8.9) | 15 (4.1) | 0.163 | 2 (7.1) | 18 (4.5) | 0.384 |
Anticoagulation | 61 (14.3) | 9 (16.1) | 52 (14.0) | 0.682 | 3 (10.7) | 58 (14.5) | 0.782 |
Antiplatelet | 405 (94.8) | 49(87.5) | 356 (96.0) | 0.016 | 23(82.1) | 382 (95.7) | 0.010 |
Statin | 400 (94.6) | 50 (89.3) | 350 (95.4) | 0.103 | 26 (92.9) | 374 (94.7) | 0.658 |
Interval time from stroke onset to admission, h | 7.0(3.5-24.0) | 5(4.0-19.8) | 8.0(3.5-24.0) | 0.110 | 5.5(4.0-22.8) | 8.0(3.5-24.0) | 0.481 |
Interval time from admission to blood sampling, h | 34.5(18.6-44.1) | 23.8(14.5-41.9) | 35.2(19.1-44.2) | 0.023 | 22.1(15.1-41.2) | 34.8(18.9-44.1) | 0.129 |