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Table 3 Univariate and multivariate logistic analysis of serum homocysteine level predicting for HT and PH

From: Higher serum homocysteine levels are associated with an increased risk of hemorrhagic transformation in patients with acute ischemic stroke

 

Univariate analysis

Multivariate analysis, adjusted OR (95% CI), P value

unadjusted OR (95% CI), P value

Model 1

Model 2

HT

   

Homocysteine (per 1 μmol/L increment)

1.026(1.002-1.050), 0.034

1.028(1.003-1.053), 0.027

1.029(1.003-1.055), 0.028

Homocysteine Levels

   

<15.5μmol/L

Reference

Reference

Reference

≥15.5μmol/L

2.073(1.174-3.659), 0.012

2.194(1.201-4.007), 0.011

1.902(1.022-3.539), 0.042

PH

   

Homocysteine (per 1 μmol/L increment)

1.037(1.011-1.064), 0.005

1.038(1.011-1.065), 0.006

1.041(1.013-1.070), 0.005

Homocysteine Levels

   

<15.5μmol/L

Reference

Reference

Reference

≥15.5μmol/L

3.388(1.542-7.445), 0.002

3.443(1.503-7.887), 0.003

3.073(1.327-7.120), 0.009

  1. HT, hemorrhagic transformation; PH, parenchyma hemorrhage; OR, odds ratio; CI, confidence interval
  2. Model 1: adjusted for sex and age
  3. Model 2: adjusted for sex, age, NIHSS on admission, atrial fibrillation and TOAST classification of stroke etiology, and interval time from admission to blood sampling