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Table 3 Univariate model of prognostic factors for mortality among TBI patients admitted to the ICU.

From: Epidemiological and clinical characteristics predictive of ICU mortality of patients with traumatic brain injury treated at a trauma referral hospital – a cohort study

Prognostic factors

N of the model

OR (95% CI) for mortalitya

p valueb

Age (years)

1114

1.008 (1.002–1.015)

0.016

Trauma mechanism

1114

  

Physical Aggression

Ref

 

GSW/SW

2.985 (1.645–5.415)

0.000

Run over

2.023 (1.198–3.417)

0.008

Cyclist

2.822 (1.409–5.649)

0.003

Collision

1.068 (0.562–2.027)

0.842

Motorbike

1.078 (0.636–1.827)

0.779

SLF

1.495 (0.91–2.458)

0.113

OLF

1.311 (0.754–2.277)

0.337

Apache II score

1114

1.180 (1.155–1.204)

< 0.001

Worst Glasgow Coma Scale score in the first 24 h

1114

0.730 (0.700–0.760)

< 0.001

Classification of Severity of TBI by the worst GCS in the first 24 h

1114

  

Severe (GCS 3 to 8)

 

Ref

 

Moderate (GCS 9 to 12)

 

2.629 (1.478–4.677)

0,001

Mild (GCS 13 to 15)

 

15,413 (9,778–24,295)

< 0,001

SOFA score in the first 24 h

974

1.400 (1.330–1.473)

< 0.001

Number of injuries on cranial CT

1114

  

None

Ref

 

One

3.250 (1.146–9.218)

0.027

Two

4.099 (1.414–11.883)

0.009

Three

10.969 (3.602–33.406)

< 0.001

The presence of each of brain injury evidenced on cranial CT compared to having no injuries on CT

   

Cerebral contusion (ref: 43 patients without injury)

210

3.596 (1.216–10.636)

0.021

DAI (ref: 43 patients without injury)

90

1.706 (0.463–6294)

0.422

Fracture and/or depression (ref: 43 patients without injury)

142

4.039 (1.323–12.335)

0.014

SAH (ref: 43 patients without injury)

422

5.394 (1.887–15.420)

0.002

SDH (ref: 43 patients without injury)

444

4.839 (1.694–13.824)

0.003

EDH (ref: 43 patients without injury)

194

1.842 (0.603–5.634)

0.284

IPH (ref: 43 patients without injury)

192

3.221 (1.079–9.619)

0.036

Haemoventriculum (ref: 43 patients without injury)

62

13.406 (3.393–5 2.977)

< 0.0001

Cerebral edema (ref: 43 patients without injury)

98

21.794 (6.715–70.732)

< 0.001

Ischaemia (ref: 43 patients without injury)

51

29.250 (4.364–196.069)

< 0.001

Pneumocephalus (ref: 43 patients without injury)

56

1.773 (2.86–10.990)

0.539

Presence of trauma in another segment in addition to the skull

1114

1.008 (0.754–1.348)

0.957

Number of injured segments in addition to TBI

1114

  

None

Ref

 

One

0.891 (0.620–1.280)

0.531

Two

1.425 (0.908–2.238)

0.124

Three or more

0.683 (0.293–1.591)

0.377

Injury follow-up in addition to TBI

   

Associated thorax injury (ref: absence of thoracic injury)

1114

1.727 (1.192–2.501)

0.004

Associated abdominal injury (ref: absence of abdominal injury)

1114

1.373 (0.777–2.427)

0.275

Associated pelvis injury (ref: absence of pelvis injury)

1114

0.714 (0.198–2.577)

0.607

Associated MRT (ref: absence of MRT)

1114

0.891 (0.488–1.625)

0.706

Associated limb injury (ref: absence of limb injury)

1114

1.020 (0.677–1.536)

0.925

Associated face and/or neck injury (except spine) (ref: absence of face/neck injury)

1114

0.295 (0.146–0.596)

< 0.001

  1. Abbreviations: TBI, traumatic brain injury; ICU, intensive care unit; OR, odds ratio; GSW, Gunshot wound; SW, Stab wound; SLF, Same-level fall; OLF, Fall from height; APACHE, Acute Physiology and Chronic Health Evaluation; CT, computed tomography; DAI, Diffuse axonal injury; SAH, Subarachnoid haemorrhage; SDH, subdural haematoma; EDH, epidural haematoma; IPH, Intraparenchymal haemorrhage
  2. a Odds ratio (OR) and 95% confidence interval of the OR (95% CI) of the univariate binary logistic regression model for mortality
  3. b Significant, Wald test of the logistic regression model